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Literature summary for 1.1.1.40 extracted from

  • Katagiri, T.; Amao, Y.
    Trivalent metal ions promote the malic enzyme-catalyzed building of carbon-carbon bonds from CO2 and pyruvate (2020), New J. Chem., 44, 17208-17214 .
No PubMed abstract available
Search for more literature for 1.1.1.40

Inhibitors

Inhibitors Comment Organism Structure
Ca2+ great inhibition Gallus gallus
Co2+ great inhibition Gallus gallus
Zn2+ great inhibition Gallus gallus

Metals/Ions

Metals/Ions Comment Organism Structure
Al3+ addition of trivalent aluminium ions (more than 0.1 mM) accelerates enzyme-catalyzed carboxylation of pyruvate with CO2 Gallus gallus
Fe3+ addition of trivalent iron ions (less than 0.01 mM) accelerates enzyme-catalyzed carboxylation of pyruvate with CO2 Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-malate + NADP+ Gallus gallus
-
 pyruvate + CO2 + NADPH + H+
-
 r
Oxaloacetate Gallus gallus
-
 Pyruvate + CO2
-
 r
Pyruvate + CO2 Gallus gallus
-
 Oxaloacetate
-
 r
pyruvate + CO2 + NADPH + H+ Gallus gallus
-
 (S)-malate + NADP+
-
 r

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-malate + NADP+
-
 Gallus gallus pyruvate + CO2 + NADPH + H+
-
 r
Oxaloacetate
-
 Gallus gallus Pyruvate + CO2
-
 r
Pyruvate + CO2
-
 Gallus gallus Oxaloacetate
-
 r
pyruvate + CO2 + NADPH + H+
-
 Gallus gallus (S)-malate + NADP+
-
 r

Synonyms

Synonyms Comment Organism
malic enzyme
-
 Gallus gallus

Cofactor

Cofactor Comment Organism Structure
NADP+
-
 Gallus gallus
NADPH
-
 Gallus gallus