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Literature summary for 1.1.1.40 extracted from

  • Drincovich, M.F.; Casati, P.; Andreo, C.S.
    NADP-malic enzyme from plants: a ubiquitous enzyme involved in different metabolic pathways (2001), FEBS Lett., 490, 1-6.
    View publication on PubMed
Search for more literature for 1.1.1.40

Inhibitors

Inhibitors Comment Organism Structure
malate no inhibition at pH 7.0 Egeria densa
malate no inhibition at pH 7.0 Flaveria floridana
malate inhibition at pH 7.0 Haloxylon persicum
malate no inhibition at pH 7.0 Mesembryanthemum crystallinum
malate no inhibition at pH 7.0 Triticum aestivum
malate inhibition at pH 7.0 Zea mays

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00315
-
 NADP+
-
 Haloxylon persicum
0.0086
-
 NADP+
-
 Zea mays
0.0099
-
 NADP+
-
 Mesembryanthemum crystallinum
0.012
-
 NADP+
-
 Flaveria floridana
0.037
-
 NADP+
-
 Triticum aestivum
0.0472
-
 NADP+
-
 Egeria densa
0.08
-
 L-malate
-
 Haloxylon persicum
0.19
-
 L-malate
-
 Zea mays
0.35
-
 L-malate
-
 Mesembryanthemum crystallinum
0.46
-
 L-malate
-
 Flaveria floridana
0.96
-
 L-malate
-
 Triticum aestivum
4.5
-
 L-malate
-
 Egeria densa

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Solanum lycopersicum 5829
-
cytosol
-
 Mesembryanthemum crystallinum 5829
-
plastid
-
 Zea mays 9536
-
plastid
-
 Flaveria floridana 9536
-
plastid
-
 Haloxylon persicum 9536
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Solanum lycopersicum
Mg2+
-
 Mesembryanthemum crystallinum
Mg2+ Km: 0.005-0.16 mM Flaveria floridana
Mg2+ Km: 0.00146 mM Egeria densa
Mg2+ Km: 0.011-3.5 mM Haloxylon persicum
Mg2+ Km: 0.006-0.2 mM Triticum aestivum
Mg2+ Km: 0.05-0.23 mM Zea mays

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
62000
-
 x * 62000, SDS-PAGE Zea mays
62000
-
 x * 62000, SDS-PAGE Flaveria floridana
64000
-
 x * 64000, SDS-PAGE Mesembryanthemum crystallinum
67000
-
 x * 67000, SDS-PAGE Haloxylon persicum
72000
-
 x * 72000, SDS-PAGE Triticum aestivum
72000
-
 x * 72000, SDS-PAGE Egeria densa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-malate + NADP+ Zea mays enzyme plays a specialized role in bundle sheath chloroplasts, where it provides CO2 for fixation by EC 4.1.1.39 pyruvate + CO2 + NADPH
-
 ?
(S)-malate + NADP+ Flaveria floridana enzyme plays a specialized role in bundle sheath chloroplasts, where it provides CO2 for fixation by EC 4.1.1.39 pyruvate + CO2 + NADPH
-
 ?
(S)-malate + NADP+ Haloxylon persicum enzyme plays a specialized role in bundle sheath chloroplasts, where it provides CO2 for fixation by EC 4.1.1.39 pyruvate + CO2 + NADPH
-
 ?

Organism

Organism UniProt Comment Textmining
Aloe arborescens
-
-
-
Apium graveolens
-
-
-
Egeria densa
-
-
-
Flaveria bidentis
-
-
-
Flaveria floridana
-
-
-
Haloxylon persicum
-
-
-
Mesembryanthemum crystallinum
-
-
-
Populus sp.
-
-
-
Solanum lycopersicum
-
-
-
Triticum aestivum
-
-
-
Zea mays
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
bundle sheath
-
 Flaveria floridana
-
bundle sheath
-
 Haloxylon persicum
-
leaf
-
 Egeria densa
-
leaf etiolated Zea mays
-
root
-
 Zea mays
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-malate + NADP+
-
 Triticum aestivum pyruvate + CO2 + NADPH
-
 ?
(S)-malate + NADP+
-
 Zea mays pyruvate + CO2 + NADPH
-
 ?
(S)-malate + NADP+
-
 Mesembryanthemum crystallinum pyruvate + CO2 + NADPH
-
 ?
(S)-malate + NADP+
-
 Flaveria floridana pyruvate + CO2 + NADPH
-
 ?
(S)-malate + NADP+
-
 Haloxylon persicum pyruvate + CO2 + NADPH
-
 ?
(S)-malate + NADP+
-
 Egeria densa pyruvate + CO2 + NADPH
-
 ?
(S)-malate + NADP+ enzyme plays a specialized role in bundle sheath chloroplasts, where it provides CO2 for fixation by EC 4.1.1.39 Zea mays pyruvate + CO2 + NADPH
-
 ?
(S)-malate + NADP+ enzyme plays a specialized role in bundle sheath chloroplasts, where it provides CO2 for fixation by EC 4.1.1.39 Flaveria floridana pyruvate + CO2 + NADPH
-
 ?
(S)-malate + NADP+ enzyme plays a specialized role in bundle sheath chloroplasts, where it provides CO2 for fixation by EC 4.1.1.39 Haloxylon persicum pyruvate + CO2 + NADPH
-
 ?

Subunits

Subunits Comment Organism
? x * 72000, SDS-PAGE Triticum aestivum
? x * 72000, SDS-PAGE Egeria densa
? x * 62000, SDS-PAGE Zea mays
? x * 62000, SDS-PAGE Flaveria floridana
? x * 67000, SDS-PAGE Haloxylon persicum
? x * 64000, SDS-PAGE Mesembryanthemum crystallinum

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2
-
-
 Triticum aestivum
7.2
-
-
 Mesembryanthemum crystallinum
7.3
-
-
 Triticum aestivum
7.3
-
-
 Egeria densa
7.5
-
-
 Flaveria floridana
8
-
-
 Zea mays
8.2
-
-
 Haloxylon persicum

Cofactor

Cofactor Comment Organism Structure
NADP+ cofactor Triticum aestivum
NADP+ cofactor Zea mays
NADP+ cofactor Solanum lycopersicum
NADP+ cofactor Mesembryanthemum crystallinum
NADP+ cofactor Flaveria floridana
NADP+ cofactor Haloxylon persicum
NADP+ cofactor Egeria densa