Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
chloroplast | chloroplast envelope inner membrane | Arabidopsis thaliana | 9507 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-malate + NAD+ | Arabidopsis thaliana | - |
oxaloacetate + NADH + H+ | - |
r | |
oxaloacetate + NADH + H+ | Arabidopsis thaliana | - |
(S)-malate + NAD+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-malate + NAD+ | - |
Arabidopsis thaliana | oxaloacetate + NADH + H+ | - |
r | |
oxaloacetate + NADH + H+ | - |
Arabidopsis thaliana | (S)-malate + NAD+ | - |
r |
Synonyms | Comment | Organism |
---|---|---|
MDH | - |
Arabidopsis thaliana |
NAD+ malate dehydrogenase | - |
Arabidopsis thaliana |
pdNAD-MDH | - |
Arabidopsis thaliana |
plastidial NAD+-dependent malate dehydrogenase | - |
Arabidopsis thaliana |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Arabidopsis thaliana | |
NADH | - |
Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
malfunction | Arabidopsis enzyme knockout mutants are embryo-lethal, and a line with lowered enzyme from gene silencing has poor growth, pale leaves, disorganized chloroplasts, and low nighttime respiration | Arabidopsis thaliana |
physiological function | the enzyme is essential during embryogenesis and seed development. The protein, but not its NAD+-dependent malate dehydrogenase enzyme activity, is required for plastid development. The enzyme is required to stabilize filamentous temperature sensitive protease FtsH12 | Arabidopsis thaliana |