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Literature summary for 1.1.1.37 extracted from

  • Yao, Y.X.; Dong, Q.L.; Zhai, H.; You, C.X.; Hao, Y.J.
    The functions of an apple cytosolic malate dehydrogenase gene in growth and tolerance to cold and salt stresses (2011), Plant Physiol. Biochem., 49, 257-264.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene cyMDH, expression in sense and antisense orientation in Solanum lycopersicum cv. Tianjinbaiguo leaves and Malus domesrtica callus tissue using the Agrobacterium strain LBA4404 transfection method, expression patterns analysis with real-time quantitative PCR, overview Malus domestica

Protein Variants

Protein Variants Comment Organism
additional information MdcyMDH overexpression favourably contributes to cell and plant growth and confers stress tolerance both in the apple callus and tomato Malus domestica

Inhibitors

Inhibitors Comment Organism Structure
additional information cyMDH is sensitive to cold and salt stresses Malus domestica

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol cytosolic NAD-dependent MDH isozyme Malus domestica 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-malate + NAD+ Malus domestica
-
oxaloacetate + NADH + H+
-
r

Organism

Organism UniProt Comment Textmining
Malus domestica A3DSX0 Orin apple
-

Source Tissue

Source Tissue Comment Organism Textmining
cell suspension culture
-
Malus domestica
-
fruit
-
Malus domestica
-
additional information MdcyMDH transcripts are highly accumulated in vigorously growing apple tissues, organs and suspension cells Malus domestica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-malate + NAD+
-
Malus domestica oxaloacetate + NADH + H+
-
r

Synonyms

Synonyms Comment Organism
cyMDH
-
Malus domestica
cytosolic malate dehydrogenase
-
Malus domestica
cytosolic NAD-dependent malate dehydrogenase
-
Malus domestica
L-malate:NAD-oxidoreductase
-
Malus domestica

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Malus domestica
NADH
-
Malus domestica

Expression

Organism Comment Expression
Malus domestica cyMDH expression is suppressed by cold and salt stresses, quantitative expression analysis, overview down

General Information

General Information Comment Organism
physiological function cyMDH is an enzyme crucial for malic acid synthesis in the cytosol. Role of the apple cyMDH gene in growth and tolerance to cold and salt stresses. cyMDH was sensitive to cold and salt stresses. cyMDH overexpression favourably contributes to cell and plant growth and confers stress tolerance in the apple Malus domestica