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Literature summary for 1.1.1.36 extracted from

  • Abd-El-haleem, D.; Amara, A.; Zaki, S.; Abulhamd, A.; Abulreesh, G.
    Biosynthesis of biodegradable polyhydroxyalkanotes biopolymers in genetically modified yeasts (2007), Int. J. Environ. Sci. Technol., 4, 513-520.
No PubMed abstract available

Cloned(Commentary)

Cloned (Comment) Organism
gene phbB, functional expression of the phaABCRe operon containing genes phbA, phbB and phbC of the PHA biosynthetic pathway of Ralstonia eutropha, which encode beta-ketothiolase, NADPH-linked acetoacetyl-CoA reductase and PHA synthase, respectively, in Saccharomyces cerevisiae strain INVSc1/PHA1 and in non-convenient Kloeckera spp. strain KY1/PHA, reconstruction of the PHA biosynthetic pathway leading to accumulation of poly-3-hydroxybutyrate and copolymer poly-(3-hydroxybutyrate-co-poly-3-hydroxyvalerate), respectively, overview Cupriavidus necator

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(R)-3-hydroxybutyryl-CoA + NADPH + H+ Cupriavidus necator
-
3-oxobutyryl-CoA + NADP+
-
r

Organism

Organism UniProt Comment Textmining
Cupriavidus necator
-
gene phbB
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Cupriavidus necator

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(R)-3-hydroxybutyryl-CoA + NADPH + H+
-
Cupriavidus necator 3-oxobutyryl-CoA + NADP+
-
r

Synonyms

Synonyms Comment Organism
NADPH-linked acetoacetyl-CoA reductase
-
Cupriavidus necator
PhbB
-
Cupriavidus necator

Cofactor

Cofactor Comment Organism Structure
NADP+
-
Cupriavidus necator
NADPH
-
Cupriavidus necator