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Literature summary for 1.1.1.35 extracted from

  • Liu, W.; Chen, G.Q.
    Production and characterization of medium-chain-length polyhydroxyalkanoate with high 3-hydroxytetradecanoate monomer content by fadB and fadA knockout mutant of Pseudomonas putida KT2442 (2007), Appl. Microbiol. Biotechnol., 76, 1153-1159.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information construction of a deletion mutant of gene fadB encoding the enzyme, the mutant shows decreased production of medium-chain-length polyhydroxyalkanoates, e.g. of 3-hydroxyhexanoate, 3- hydroxyoctanoate, 3-hydroxydecanoate, 3-hydroxydodecanoate, and 3-hydroxytetradecanoate, overview Pseudomonas putida

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-3-hydroxyacyl-CoA + NAD+ Pseudomonas putida the enzyme is involved in the biosynthesis of medium-chain-length polyhydroxyalkanoates, overview 3-oxoacyl-CoA + NADH + H+
-
?
(S)-3-hydroxyacyl-CoA + NAD+ Pseudomonas putida KT 2442 the enzyme is involved in the biosynthesis of medium-chain-length polyhydroxyalkanoates, overview 3-oxoacyl-CoA + NADH + H+
-
?

Organism

Organism UniProt Comment Textmining
Pseudomonas putida
-
gene fadB
-
Pseudomonas putida KT 2442
-
gene fadB
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-3-hydroxyacyl-CoA + NAD+
-
Pseudomonas putida 3-oxoacyl-CoA + NADH + H+
-
?
(S)-3-hydroxyacyl-CoA + NAD+ the enzyme is involved in the biosynthesis of medium-chain-length polyhydroxyalkanoates, overview Pseudomonas putida 3-oxoacyl-CoA + NADH + H+
-
?
(S)-3-hydroxyacyl-CoA + NAD+
-
Pseudomonas putida KT 2442 3-oxoacyl-CoA + NADH + H+
-
?
(S)-3-hydroxyacyl-CoA + NAD+ the enzyme is involved in the biosynthesis of medium-chain-length polyhydroxyalkanoates, overview Pseudomonas putida KT 2442 3-oxoacyl-CoA + NADH + H+
-
?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Pseudomonas putida