BRENDA - Enzyme Database
show all sequences of 1.1.1.331

Expressed sequence tags and molecular cloning and characterization of gene encoding pinoresinol/lariciresinol reductase from Podophyllum hexandrum

Wankhede, D.P.; Biswas, D.K.; Rajkumar, S.; Sinha, A.K.; Protoplasma 250, 1239-1249 (2013)

Data extracted from this reference:

Cloned(Commentary)
Cloned (Commentary)
Organism
gene PhSDH, sequence comparisons, semiquantitative RT-PCR expression analysis
Sinopodophyllum hexandrum
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
(-)-secoisolariciresinol + 2 NAD+
Sinopodophyllum hexandrum
-
(-)-matairesinol + 2 NADH + 2 H+
-
-
?
Organism
Organism
UniProt
Commentary
Textmining
Sinopodophyllum hexandrum
A3F5F0
cvs. Yada and Jobrang
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
leaf
-
Sinopodophyllum hexandrum
-
additional information
expression pattern of PhSDH in different tissues and under abiotic stress, overview. PhSDH has the lowest expression in leaf compared to stem and root
Sinopodophyllum hexandrum
-
rhizome
-
Sinopodophyllum hexandrum
-
root
-
Sinopodophyllum hexandrum
-
stem
-
Sinopodophyllum hexandrum
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
(-)-secoisolariciresinol + 2 NAD+
-
743768
Sinopodophyllum hexandrum
(-)-matairesinol + 2 NADH + 2 H+
-
-
-
?
Synonyms
Synonyms
Commentary
Organism
PhSDH
-
Sinopodophyllum hexandrum
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
-
Sinopodophyllum hexandrum
Cloned(Commentary) (protein specific)
Commentary
Organism
gene PhSDH, sequence comparisons, semiquantitative RT-PCR expression analysis
Sinopodophyllum hexandrum
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
-
Sinopodophyllum hexandrum
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
(-)-secoisolariciresinol + 2 NAD+
Sinopodophyllum hexandrum
-
(-)-matairesinol + 2 NADH + 2 H+
-
-
?
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
leaf
-
Sinopodophyllum hexandrum
-
additional information
expression pattern of PhSDH in different tissues and under abiotic stress, overview. PhSDH has the lowest expression in leaf compared to stem and root
Sinopodophyllum hexandrum
-
rhizome
-
Sinopodophyllum hexandrum
-
root
-
Sinopodophyllum hexandrum
-
stem
-
Sinopodophyllum hexandrum
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
(-)-secoisolariciresinol + 2 NAD+
-
743768
Sinopodophyllum hexandrum
(-)-matairesinol + 2 NADH + 2 H+
-
-
-
?
Expression
Organism
Commentary
Expression
Sinopodophyllum hexandrum
the enzyme expression is induced by wounding and methyl jasmonate, while UV light induces short peaks of the enzyme expression after 6 h intervals, expression pattern of PhSDH in different tissues and under abiotic stress, overview
up
General Information
General Information
Commentary
Organism
metabolism
the enzyme is part of the podophyllotoxin, PPT, biosynthetic pathway, overview. Podophyllotoxin is an important aryltetralin lignan, that possesses antitumor and antihyperlipidemic activities
Sinopodophyllum hexandrum
General Information (protein specific)
General Information
Commentary
Organism
metabolism
the enzyme is part of the podophyllotoxin, PPT, biosynthetic pathway, overview. Podophyllotoxin is an important aryltetralin lignan, that possesses antitumor and antihyperlipidemic activities
Sinopodophyllum hexandrum
Expression (protein specific)
Organism
Commentary
Expression
Sinopodophyllum hexandrum
the enzyme expression is induced by wounding and methyl jasmonate, while UV light induces short peaks of the enzyme expression after 6 h intervals, expression pattern of PhSDH in different tissues and under abiotic stress, overview
up
Other publictions for EC 1.1.1.331
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
743611
Shiraishi
De novo transcriptomes of For ...
Forsythia koreana
PLoS ONE
11
e0164805
2016
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1
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-
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-
-
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1
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9
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3
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1
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4
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1
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1
1
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1
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3
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1
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1
3
3
1
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-
743278
Arneaud
Investigation and expression ...
Phialocephala podophylli, Phialocephala podophylli PPE7, Podophyllum peltatum
Mol. Biotechnol.
57
961-973
2015
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2
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3
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8
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2
2
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2
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5
5
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741681
Kuo
Bioconversion of pinoresinol ...
Dysosma pleiantha
Appl. Environ. Microbiol.
80
2687-2692
2014
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1
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1
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1
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5
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1
2
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2
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742033
Morimoto
Seasonal alteration in amount ...
Forsythia x intermedia
Biol. Pharm. Bull.
36
1519-1523
2013
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1
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3
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1
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2
2
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743768
Wankhede
Expressed sequence tags and m ...
Sinopodophyllum hexandrum
Protoplasma
250
1239-1249
2013
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1
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1
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6
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5
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1
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5
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1
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1
1
1
1
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720203
Lan
-
Molecular cloning and characte ...
Dysosma tsayuensis
J. Med. Plant Res.
4
484-489
2010
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1
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1
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1
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5
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1
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720614
Moinuddin
Secoisolariciresinol dehydroge ...
Podophyllum peltatum
Org. Biomol. Chem.
4
808-816
2006
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3
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4
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1
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1
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1
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1
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719829
Youn
Crystal structures of apo-form ...
Podophyllum peltatum
J. Biol. Chem.
280
12917-12926
2005
-
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1
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4
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1
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720350
Okunishi
-
Stereochemistry of matairesino ...
Daphne genkwa, Daphne odora
J. Wood Sci.
50
77-81
2004
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719805
Xia
Secoisolariciresinol dehydroge ...
Forsythia x intermedia, Podophyllum peltatum
J. Biol. Chem.
276
12614-12623
2001
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2
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2
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8
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2
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2
2
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