BRENDA - Enzyme Database
show all sequences of 1.1.1.331

Seasonal alteration in amounts of lignans and their glucosides and gene expression of the relevant biosynthetic enzymes in the Forsythia suspense leaf

Morimoto, K.; Satake, H.; Biol. Pharm. Bull. 36, 1519-1523 (2013)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
(-)-secoisolariciresinol + 2 NAD+
Forsythia x intermedia
-
(-)-matairesinol + 2 NADH + 2 H+
-
-
?
Organism
Organism
UniProt
Commentary
Textmining
Forsythia x intermedia
Q94KL7
Forsythia suspensa x Forsythia viridissima
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
leaf
seasonal alteration in amounts of major lignans, such as pinoresinol, matairesinol, and arctigenin, analysis of gene expression profile of secoisolariciresinol dehydrogenase (SIRD) and other related enzymes in the leaves of Forsythia suspense from April to November. The SIRD expression is prominent from April to May, not detected in June to July, and then increases again from September to November. All of the lignans in the leaf continuously increase from April to June, reach the maximal level in June, and then decrease
Forsythia x intermedia
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
(-)-secoisolariciresinol + 2 NAD+
-
742033
Forsythia x intermedia
(-)-matairesinol + 2 NADH + 2 H+
-
-
-
?
Synonyms
Synonyms
Commentary
Organism
SirD
-
Forsythia x intermedia
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
-
Forsythia x intermedia
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
-
Forsythia x intermedia
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
(-)-secoisolariciresinol + 2 NAD+
Forsythia x intermedia
-
(-)-matairesinol + 2 NADH + 2 H+
-
-
?
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
leaf
seasonal alteration in amounts of major lignans, such as pinoresinol, matairesinol, and arctigenin, analysis of gene expression profile of secoisolariciresinol dehydrogenase (SIRD) and other related enzymes in the leaves of Forsythia suspense from April to November. The SIRD expression is prominent from April to May, not detected in June to July, and then increases again from September to November. All of the lignans in the leaf continuously increase from April to June, reach the maximal level in June, and then decrease
Forsythia x intermedia
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
(-)-secoisolariciresinol + 2 NAD+
-
742033
Forsythia x intermedia
(-)-matairesinol + 2 NADH + 2 H+
-
-
-
?
General Information
General Information
Commentary
Organism
metabolism
the enzyme is involved in the lignan biosynthetic pathways in Forsythia, overview
Forsythia x intermedia
physiological function
the enzyme SIRD is involved in the biosynthesis of lignan matairesinol in Forsythia. The leaves show seasonal alteration in amounts of major lignans, such as pinoresinol, matairesinol, and arctigenin, gene expression profile of secoisolariciresinol dehydrogenase (SIRD) and other related enzymes in the leaves of Forsythia suspense from April to November: all of the lignans in the leaf continuously increase from April to June, reach the maximal level in June, and then decrease
Forsythia x intermedia
General Information (protein specific)
General Information
Commentary
Organism
metabolism
the enzyme is involved in the lignan biosynthetic pathways in Forsythia, overview
Forsythia x intermedia
physiological function
the enzyme SIRD is involved in the biosynthesis of lignan matairesinol in Forsythia. The leaves show seasonal alteration in amounts of major lignans, such as pinoresinol, matairesinol, and arctigenin, gene expression profile of secoisolariciresinol dehydrogenase (SIRD) and other related enzymes in the leaves of Forsythia suspense from April to November: all of the lignans in the leaf continuously increase from April to June, reach the maximal level in June, and then decrease
Forsythia x intermedia
Other publictions for EC 1.1.1.331
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
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Shiraishi
De novo transcriptomes of For ...
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e0164805
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3
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2
2
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5
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741681
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Dysosma pleiantha
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5
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742033
Morimoto
Seasonal alteration in amount ...
Forsythia x intermedia
Biol. Pharm. Bull.
36
1519-1523
2013
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3
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1
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2
2
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Wankhede
Expressed sequence tags and m ...
Sinopodophyllum hexandrum
Protoplasma
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1239-1249
2013
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1
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6
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5
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1
1
1
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720203
Lan
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Molecular cloning and characte ...
Dysosma tsayuensis
J. Med. Plant Res.
4
484-489
2010
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1
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1
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1
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720614
Moinuddin
Secoisolariciresinol dehydroge ...
Podophyllum peltatum
Org. Biomol. Chem.
4
808-816
2006
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3
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4
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719829
Youn
Crystal structures of apo-form ...
Podophyllum peltatum
J. Biol. Chem.
280
12917-12926
2005
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1
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4
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720350
Okunishi
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Stereochemistry of matairesino ...
Daphne genkwa, Daphne odora
J. Wood Sci.
50
77-81
2004
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719805
Xia
Secoisolariciresinol dehydroge ...
Forsythia x intermedia, Podophyllum peltatum
J. Biol. Chem.
276
12614-12623
2001
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2
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