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Literature summary for 1.1.1.323 extracted from
- Substrate specificity of monoterpenol dehydrogenases from Foeniculum vulgare and Tanacetum vulgare (1980), Phytochemistry, 19, 1343-1347.
No PubMed abstract available
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.04 | - |
(+)-thujan-3-ol | pH 8.0, 30°C | Tanacetum vulgare |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 66500 | - |
gel filtration | Tanacetum vulgare |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (+)-thujan-3-ol + NAD(P)+ | Tanacetum vulgare | - |
(+)-thujan-3-one + NAD(P)H + H+ | - |
? | |
| additional information | Tanacetum vulgare | leaves of Tanacetum vulgare catalyse the pyridine nucleotide-dependent dehydrogenation of D-3-thujanol to D-3-thujone | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Tanacetum vulgare | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| native enzyme partially by gel filtration | Tanacetum vulgare |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leaf | - |
Tanacetum vulgare | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| the partially purified enzyme is most stable in 50 mM sodium phosphate buffer, pH 8.0 | Tanacetum vulgare |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (+)-thujan-3-ol + NAD(P)+ | - |
Tanacetum vulgare | (+)-thujan-3-one + NAD(P)H + H+ | - |
? | |
| additional information | leaves of Tanacetum vulgare catalyse the pyridine nucleotide-dependent dehydrogenation of D-3-thujanol to D-3-thujone | Tanacetum vulgare | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TDH | - |
Tanacetum vulgare |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Tanacetum vulgare |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
- |
Tanacetum vulgare |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 6.7 | 9.3 | 50% of maximal activity at pH 6.7 and pH 9.3 | Tanacetum vulgare |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD(P)+ | TDH shows a slight preference for NAD+ over NADP+ as cofactor | Tanacetum vulgare | |
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