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Literature summary for 1.1.1.30 extracted from

  • Davuluri, G.; Song, P.; Liu, Z.; Wald, D.; Sakaguchi, T.F.; Green, M.R.; Devireddy, L.
    Inactivation of 3-hydroxybutyrate dehydrogenase 2 delays zebrafish erythroid maturation by conferring premature mitophagy (2016), Proc. Natl. Acad. Sci. USA, 113, E1460-E1469.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(R)-3-hydroxybutanoate + NAD+ Danio rerio
-
 acetoacetate + NADH + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Danio rerio Q561X9
-
-

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
 Danio rerio
-
erythrocyte
-
 Danio rerio
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(R)-3-hydroxybutanoate + NAD+
-
 Danio rerio acetoacetate + NADH + H+
-
 ?

Synonyms

Synonyms Comment Organism
3-hydroxybutyrate dehydrogenase 2
-
 Danio rerio
BDH2
-
 Danio rerio

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Danio rerio

General Information

General Information Comment Organism
malfunction enzyme inactivation in developing zebrafish embryo results in heme deficiency and delays erythrocyte maturation Danio rerio