Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,4-Dichlorophenoxyacetic acid | inhibits the enzyme, in vivo treatment of the animals with 2,4-dichlorophenoxyacetic acid leads to strong decrease of triglycerides level and HDL cholesterol and an increase in GOT level and LDL cholesterol, and necrosis of seminiferous tubules cells in testis, hyperplasia of hepatocytes in liver and presence of multinucleated giant cells in brain, overview | Jaculus orientalis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.21 | - |
NAD+ | pH 8.0, 25°C | Jaculus orientalis | |
1.6 | - |
(R)-3-hydroxybutanoate | pH 8.0, 25°C | Jaculus orientalis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Jaculus orientalis | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-3-hydroxybutanoate + NAD+ | Jaculus orientalis | - |
acetoacetate + NADH | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Jaculus orientalis | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Jaculus orientalis | - |
liver | - |
Jaculus orientalis | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-3-hydroxybutanoate + NAD+ | - |
Jaculus orientalis | acetoacetate + NADH | - |
r |
Synonyms | Comment | Organism |
---|---|---|
BDH | - |
Jaculus orientalis |
D-3-hydroxybutyrate dehydrogenase | - |
Jaculus orientalis |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Jaculus orientalis |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
assay at | Jaculus orientalis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Jaculus orientalis |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
3.38 | - |
2,4-Dichlorophenoxyacetic acid | pH 8.0, 25°C, versus NAD+ | Jaculus orientalis | |
5.74 | - |
2,4-Dichlorophenoxyacetic acid | pH 8.0, 25°C, versus (R)-3-hydroxybutanoate | Jaculus orientalis |