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Literature summary for 1.1.1.284 extracted from

  • Gutheil, W.G.; Kasimoglu, E.; Nicholson, P.C.
    Induction of glutathione-dependent formaldehyde dehydrogenase activity in Escherichia coli and Hemophilus influenza (1997), Biochem. Biophys. Res. Commun., 238, 693-696.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
formaldehyde + glutathione + NAD+ Haemophilus influenzae inducible enzyme, at least one function of the enzyme in Gram-negative bacteria is to detoxify exogenous formaldehyde encountered in their environment S-formylglutathione + NADH + H+
-
 ?
formaldehyde + glutathione + NAD+ Escherichia coli inducible enzyme, at least one function of the enzyme in Gram-negative bacteria is to detoxify exogenous formaldehyde encountered in their environment S-formylglutathione + NADH + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Haemophilus influenzae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
formaldehyde + glutathione + NAD+
-
 Haemophilus influenzae S-formylglutathione + NADH + H+
-
 ?
formaldehyde + glutathione + NAD+
-
 Escherichia coli S-formylglutathione + NADH + H+
-
 ?
formaldehyde + glutathione + NAD+ inducible enzyme, at least one function of the enzyme in Gram-negative bacteria is to detoxify exogenous formaldehyde encountered in their environment Haemophilus influenzae S-formylglutathione + NADH + H+
-
 ?
formaldehyde + glutathione + NAD+ inducible enzyme, at least one function of the enzyme in Gram-negative bacteria is to detoxify exogenous formaldehyde encountered in their environment Escherichia coli S-formylglutathione + NADH + H+
-
 ?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Haemophilus influenzae
NAD+
-
 Escherichia coli