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Literature summary for 1.1.1.27 extracted from

  • Hensel, R.; Mayr, U.; Fujiki, H.; Kandler, O.
    Comparative studies of lactate dehydrogenases in lactic acid bacteria. Amino-acid composition of an active-site region and chemical properties of the L-lactate dehydrogenase of Lactobacillus casei, Lactobacillus curvatus, Lactobacillus plantarum, and Lactobacillus acidophilus (1977), Eur. J. Biochem., 80, 83-92.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
iodoacetate
-
 Lacticaseibacillus casei
iodoacetate
-
 Lactobacillus acidophilus
iodoacetate no effect Latilactobacillus curvatus
p-hydroxymercuribenzoate
-
 Lacticaseibacillus casei
p-hydroxymercuribenzoate slight Lactobacillus acidophilus

Organism

Organism UniProt Comment Textmining
Lacticaseibacillus casei
-
-
-
Lactiplantibacillus plantarum
-
-
-
Lactobacillus acidophilus
-
-
-
Latilactobacillus curvatus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Lactiplantibacillus plantarum
-
 Lacticaseibacillus casei
-
 Latilactobacillus curvatus
-
 Lactobacillus acidophilus

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2350
-
-
 Lactiplantibacillus plantarum
2460
-
-
 Lactobacillus acidophilus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-lactate + NAD+
-
 Lactiplantibacillus plantarum pyruvate + NADH + H+
-
 r
(S)-lactate + NAD+
-
 Lacticaseibacillus casei pyruvate + NADH + H+
-
 r
(S)-lactate + NAD+
-
 Latilactobacillus curvatus pyruvate + NADH + H+
-
 r
(S)-lactate + NAD+
-
 Lactobacillus acidophilus pyruvate + NADH + H+
-
 r
pyruvate + NADH + H+
-
 Lactiplantibacillus plantarum (S)-lactate + NAD+
-
 r
pyruvate + NADH + H+
-
 Lacticaseibacillus casei (S)-lactate + NAD+
-
 r
pyruvate + NADH + H+
-
 Latilactobacillus curvatus (S)-lactate + NAD+
-
 r
pyruvate + NADH + H+
-
 Lactobacillus acidophilus (S)-lactate + NAD+
-
 r

Cofactor

Cofactor Comment Organism Structure
NAD+ coenzyme Lactiplantibacillus plantarum
NAD+ coenzyme Lacticaseibacillus casei
NAD+ coenzyme Latilactobacillus curvatus
NAD+ coenzyme Lactobacillus acidophilus
NADH coenzyme Lactiplantibacillus plantarum
NADH coenzyme Lacticaseibacillus casei
NADH coenzyme Latilactobacillus curvatus
NADH coenzyme Lactobacillus acidophilus