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Literature summary for 1.1.1.213 extracted from

  • Wiebe, J.P.; Souter, L.; Zhang, G.
    Dutasteride affects progesterone metabolizing enzyme activity/expression in human breast cell lines resulting in suppression of cell proliferation and detachment (2006), J. Steroid Biochem. Mol. Biol., 100, 129-140.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
additional information dutasteride alters the expression level of the enzyme in breast cancer cells, the inhibitor affects the 5alpha-progesterone reductase and the progesterone metabolism, overview Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
breast cancer cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
3-alpha hydroxysteroid oxidoreductase
-
Homo sapiens
3-alpha-HSO
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Homo sapiens