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Literature summary for 1.1.1.21 extracted from

  • Yabe-Nishimura, C.; Nishinaka, T.; Iwata, K.; Seo, H.G.
    Up-regulation of aldose reductase by the substrate, methylglyoxal (2003), Chem. Biol. Interact., 143-144, 317-323.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
ponalrestat cytotoxic effect of methylglyoxal is enhanced in presence of ponalrestat Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus protective role of enzyme against methylglyoxal induced cell damage, cytotoxic effect of methylglyoxal is enhanced in presence of ponalrestat ?
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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Source Tissue

Source Tissue Comment Organism Textmining
muscle aortic smooth muscle cell Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information protective role of enzyme against methylglyoxal induced cell damage, cytotoxic effect of methylglyoxal is enhanced in presence of ponalrestat Rattus norvegicus ?
-
 ?