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Literature summary for 1.1.1.209 extracted from

  • Lau, P.C.K.; Layne, D.S.; Williamson, D.G.
    A 3(17) alpha-hydroxysteroid dehydrogenase of female rabbit kidney cytosol. Purification and characterization of multiple forms of the enzyme (1982), J. Biol. Chem., 257, 9444-9449.
    View publication on PubMed
Search for more literature for 1.1.1.209

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Oryctolagus cuniculus 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40000
-
 female rabbit, form IB, gel filtration Oryctolagus cuniculus
41000
-
 female rabbit, forms II and III, gel filtration Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
 emale
-

Purification (Commentary)

Purification (Comment) Organism
female, 4 forms of enzyme Oryctolagus cuniculus

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Oryctolagus cuniculus
-

Storage Stability

Storage Stability Organism
-20°C Oryctolagus cuniculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
17alpha-estradiol + NAD(P)+
-
 Oryctolagus cuniculus estrone + NAD(P)H
-
 ?
17alpha-estradiol 3-glucuronide + NAD(P)+
-
 Oryctolagus cuniculus estrone 3-glucuronide + NAD(P)H
-
 ?
3alpha-hydroxy-5alpha-androstan-17-one + NAD(P)+ i.e. androsterone Oryctolagus cuniculus 5alpha-androstan-3,17-dione + NAD(P)H
-
 ?
5alpha-androstan-3alpha,17beta-diol + NAD(P)+
-
 Oryctolagus cuniculus 17beta-hydroxy-5alpha-androstan-3-one + NAD(P)H
-
 ?
epitestosterone + NAD(P)+
-
 Oryctolagus cuniculus androst-4-en-3,17-dione + NAD(P)H + H+
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 40000, female rabbit, form IB, 1 * 41000, female rabbit, forms II and III, SDS-PAGE Oryctolagus cuniculus

Cofactor

Cofactor Comment Organism Structure
NAD+ low activity Oryctolagus cuniculus
NADH low activity Oryctolagus cuniculus
NADP+ preferred Oryctolagus cuniculus
NADPH preferred Oryctolagus cuniculus