Literature summary for 1.1.1.205 extracted from

Omolabi, K.F.; Iwuchukwu, E.A.; Agoni, C.; Olotu, F.A.; Soliman, M.E.S.
A probable means to an end exploring P131 pharmacophoric scaffold to identify potential inhibitors of Cryptosporidium parvum inosine monophosphate dehydrogenase (2021), J. Mol. Model., 27, 35 .

Search for more literature for 1.1.1.205

Inhibitors

Inhibitors	Comment	Organism	Structure
2-methylquinolin-8-yl 4-methylnaphthalene-1-sulfonate	ZINC58646829	Cryptosporidium parvum
2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl 5-methylquinoline-8-sulfonate	ZINC46542062	Cryptosporidium parvum
5,6,7,8-tetrahydroquinoxalin-6-yl 8-methylquinoline-5-sulfonate	ZINC89780094	Cryptosporidium parvum
N-(2-[3-[(1E)-N-(2-aminoethoxy)ethanimidoyl]phenyl[propan-2-yl)-N'-(4-chloro-3-nitrophenyl)urea	P131	Cryptosporidium parvum

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
IMP + NAD+ + H2O	Cryptosporidium parvum	-	XMP + NADH + H+	-	?

Organism

Organism	UniProt	Comment	Textmining
Cryptosporidium parvum	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
IMP + NAD+ + H2O	-	Cryptosporidium parvum	XMP + NADH + H+	-	?

Synonyms

Synonyms	Comment	Organism
IMPDH	-	Cryptosporidium parvum
inosine monophosphate dehydrogenase	-	Cryptosporidium parvum

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Cryptosporidium parvum

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Release 2023.1 (January 2023)