Literature summary for 1.1.1.202 extracted from

Hao, J.; Lin, R.; Zheng, Z.; Sun, Y.; Liu, D.
3-Hydroxypropionaldehyde guided glycerol feeding strategy in aerobic 1,3-propanediol production by Klebsiella pneumoniae (2008), J. Ind. Microbiol. Biotechnol., 35, 1615-1624.

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Activating Compound

Activating Compound	Comment	Organism	Structure
glycerol	-	Klebsiella pneumoniae

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	when the concentration of 3-hydroxypropanal increases to a higher level in medium (ac 10 mmol/L), the activity of 1,3-propanediol oxidoreductase in cell decreases correspondingly, which leads to decrease of the 3-hydroxypropanal conversion rate, then the 3-hydroxypropanal concentration increasing is accelerated furthermore	Klebsiella pneumoniae

Organism

Organism	UniProt	Comment	Textmining
Klebsiella pneumoniae	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3-hydroxypropanal + NADH + H+	in the cell exponential growth phase, the reaction catalyzed by 1,3-propanediol oxidoreductase is the rate limiting step in 1,3-propanediol production	Klebsiella pneumoniae	propane-1,3-diol + NAD+	-	?

Synonyms

Synonyms	Comment	Organism
1,3-propanediol oxidoreductase	-	Klebsiella pneumoniae
PDOR	-	Klebsiella pneumoniae

pH Range

pH Minimum	pH Maximum	Comment	Organism
7	9	-	Klebsiella pneumoniae

Cofactor

Cofactor	Comment	Organism	Structure
NADH	-	Klebsiella pneumoniae

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Release 2023.1 (January 2023)