Any feedback?
Literature summary for 1.1.1.202 extracted from
- 1,3-Propanediol oxidoreductase production with Klebsiella pneumoniae DSM2026 (2003), World J. Microbiol. Biotechnol., 19, 659-663.
No PubMed abstract available
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| glycerol | at concentrations around 16 g/l, regulation, overview | Klebsiella pneumoniae |  |
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | Klebsiella pneumoniae is used for production of 1,3-propanediol by the enzyme which is utilized in plastic industry | Klebsiella pneumoniae |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| glycerol | at high concentration above 40 g/l, overview | Klebsiella pneumoniae | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| propane-1,3-diol + NAD+ | Klebsiella pneumoniae | key enzyme of the 1,3-propanediol production pathway, high enzyme synthesis and activity in the anaerobic growth phase with increased use of glycerol | 3-hydroxypropanal + NADH | - |
? | |
| propane-1,3-diol + NAD+ | Klebsiella pneumoniae DSM 2026 | key enzyme of the 1,3-propanediol production pathway, high enzyme synthesis and activity in the anaerobic growth phase with increased use of glycerol | 3-hydroxypropanal + NADH | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Klebsiella pneumoniae | - |
DSM2026 | - |
| Klebsiella pneumoniae DSM 2026 | - |
DSM2026 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| propane-1,3-diol + NAD+ | - |
Klebsiella pneumoniae | 3-hydroxypropanal + NADH | - |
r | |
| propane-1,3-diol + NAD+ | key enzyme of the 1,3-propanediol production pathway, high enzyme synthesis and activity in the anaerobic growth phase with increased use of glycerol | Klebsiella pneumoniae | 3-hydroxypropanal + NADH | - |
? | |
| propane-1,3-diol + NAD+ | - |
Klebsiella pneumoniae DSM 2026 | 3-hydroxypropanal + NADH | - |
r | |
| propane-1,3-diol + NAD+ | key enzyme of the 1,3-propanediol production pathway, high enzyme synthesis and activity in the anaerobic growth phase with increased use of glycerol | Klebsiella pneumoniae DSM 2026 | 3-hydroxypropanal + NADH | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 1,3-propanediol oxidoreductase | - |
Klebsiella pneumoniae |
| 1,3-propanediol-oxidoreductase | - |
Klebsiella pneumoniae |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
assay at | Klebsiella pneumoniae |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9 | - |
assay at | Klebsiella pneumoniae |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Klebsiella pneumoniae | |
| NADH | - |
Klebsiella pneumoniae | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 12.09 | - |
glycerol | pH 9.0, 25°C | Klebsiella pneumoniae | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
