Literature summary for 1.1.1.201 extracted from

Zhang, X.; Fan, D.; Hua, X.; Zhang, T.
Large-scale production of ursodeoxycholic acid from chenodeoxycholic acid by engineering 7alpha- and 7beta-hydroxysteroid dehydrogenase (2019), Bioprocess Biosyst. Eng., 42, 1537-1545 .

Search for more literature for 1.1.1.201

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3) cells	[Ruminococcus] torques

Organism

Organism	UniProt	Comment	Textmining
[Ruminococcus] torques	-	-	-
[Ruminococcus] torques ATCC 35915	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
GST-Sefinose affinity column chromatography	[Ruminococcus] torques

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
7-oxo-lithocholic acid + NADPH + H+	after a first reaction step with EC 1.1.1.159, 7alpha-hydroxysteroid dehydrogenase, from chenodeoxycholic acid	[Ruminococcus] torques	ursodeoxycholic acid + NADP+	-	?
7-oxo-lithocholic acid + NADPH + H+	after a first reaction step with EC 1.1.1.159, 7alpha-hydroxysteroid dehydrogenase, from chenodeoxycholic acid	[Ruminococcus] torques ATCC 35915	ursodeoxycholic acid + NADP+	-	?

Subunits

Subunits	Comment	Organism
?	x * 30000, SDS-PAGE	[Ruminococcus] torques

Synonyms

Synonyms	Comment	Organism
7beta-HSDH	-	[Ruminococcus] torques

Cofactor

Cofactor	Comment	Organism	Structure
NADP+	-	[Ruminococcus] torques

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Release 2023.1 (January 2023)