Characterization of fatty alcohol:NAD+ oxidoreductase from rat liver

Lee, T.C.; J. Biol. Chem. 254, 2892-2896 (1979)

Data extracted from this reference:

Inhibitors

Commentary

Organism

Structure

cyanide

-

Rattus norvegicus

additional information

not: pyrazole, sodium azide, AMP, ATP, quinacrine, iodoacetate

Rattus norvegicus

N-ethylmaleimide

-

Rattus norvegicus

KM Value [mM]

KM Value Maximum [mM]

Substrate

Commentary

Organism

Structure

0.00067

-

hexadecanol

-

Rattus norvegicus

Natural Substrates

Organism

Commentary (Nat. Sub.)

Natural Products

Commentary (Nat. Pro.)

Organism (Nat. Pro.)

Reversibility

ID

long-chain alcohol + NAD+ + H2O

Rattus norvegicus

enzyme may play an important role in regulating the cellular levels of ether-linked lipids

long-chain carboxylate + NADH

-

-

-

Substrates

Commentary Substrates

Literature (Substrates)

Organism

Products

Commentary (Products)

Literature (Products)

Organism (Products)

Reversibility

Substrate Product ID

hexadecanol + NAD+ + H2O

-

347794

Rattus norvegicus

hexadecanal + NADH

-

-

-

?

long-chain alcohol + NAD+ + H2O

maximal activity with decanol

347794

Rattus norvegicus

long-chain carboxylate + NADH

-

-

-

-

long-chain alcohol + NAD+ + H2O

C10-C18

347794

Rattus norvegicus

long-chain carboxylate + NADH

-

-

-

-

long-chain alcohol + NAD+ + H2O

enzyme may play an important role in regulating the cellular levels of ether-linked lipids

347794

Rattus norvegicus

long-chain carboxylate + NADH

-

-

-

-

Cofactor

Commentary

Organism

Structure

NAD+

absolute requirement

Rattus norvegicus

Cofactor

Commentary

Organism

Structure

NAD+

absolute requirement

Rattus norvegicus

Inhibitors

Commentary

Organism

Structure

cyanide

-

Rattus norvegicus

additional information

not: pyrazole, sodium azide, AMP, ATP, quinacrine, iodoacetate

Rattus norvegicus

N-ethylmaleimide

-

Rattus norvegicus

KM Value [mM]

KM Value Maximum [mM]

Substrate

Commentary

Organism

Structure

0.00067

-

hexadecanol

-

Rattus norvegicus

Natural Substrates

Organism

Commentary (Nat. Sub.)

Natural Products

Commentary (Nat. Pro.)

Organism (Nat. Pro.)

Reversibility

ID

long-chain alcohol + NAD+ + H2O

Rattus norvegicus

enzyme may play an important role in regulating the cellular levels of ether-linked lipids

long-chain carboxylate + NADH

-

-

-

Substrates

Commentary Substrates

Literature (Substrates)

Organism

Products

Commentary (Products)

Literature (Products)

Organism (Products)

Reversibility

ID

hexadecanol + NAD+ + H2O

-

347794

Rattus norvegicus

hexadecanal + NADH

-

-

-

?

long-chain alcohol + NAD+ + H2O

maximal activity with decanol

347794

Rattus norvegicus

long-chain carboxylate + NADH

-

-

-

-

long-chain alcohol + NAD+ + H2O

C10-C18

347794

Rattus norvegicus

long-chain carboxylate + NADH

-

-

-

-

long-chain alcohol + NAD+ + H2O

enzyme may play an important role in regulating the cellular levels of ether-linked lipids

347794

Rattus norvegicus

long-chain carboxylate + NADH

-

-

-

-

No.

1st author

Pub Med

title

organims

journal

volume

pages

year

Activating Compound

Application

Cloned(Commentary)

Crystallization (Commentary)

Engineering

General Stability

Inhibitors

KM Value [mM]

Localization

Metals/Ions

Molecular Weight [Da]

Natural Substrates/ Products (Substrates)

Organic Solvent Stability

Organism

Oxidation Stability

Posttranslational Modification

Purification (Commentary)

Reaction

Renatured (Commentary)

Source Tissue

Specific Activity [micromol/min/mg]

Storage Stability

Substrates and Products (Substrate)

Subunits

Synonyms

Temperature Optimum [°C]

Temperature Range [°C]

Temperature Stability [°C]

Turnover Number [1/s]

pH Optimum

pH Range

pH Stability

Cofactor

Ki Value [mM]

pI Value

IC50 Value

Activating Compound (protein specific)

Application (protein specific)

Cloned(Commentary) (protein specific)

Cofactor (protein specific)

Crystallization (Commentary) (protein specific)

Engineering (protein specific)

General Stability (protein specific)

IC50 Value (protein specific)

Inhibitors (protein specific)

Ki Value [mM] (protein specific)

KM Value [mM] (protein specific)

Localization (protein specific)

Metals/Ions (protein specific)

Molecular Weight [Da] (protein specific)

Natural Substrates/ Products (Substrates) (protein specific)

Organic Solvent Stability (protein specific)

Oxidation Stability (protein specific)

Posttranslational Modification (protein specific)

Purification (Commentary) (protein specific)

Renatured (Commentary) (protein specific)

Source Tissue (protein specific)

Specific Activity [micromol/min/mg] (protein specific)

Storage Stability (protein specific)

Substrates and Products (Substrate) (protein specific)

Subunits (protein specific)

Temperature Optimum [°C] (protein specific)

Temperature Range [°C] (protein specific)

Temperature Stability [°C] (protein specific)

Turnover Number [1/s] (protein specific)

pH Optimum (protein specific)

pH Range (protein specific)

pH Stability (protein specific)

pI Value (protein specific)

Expression

General Information

General Information (protein specific)

Expression (protein specific)

KCat/KM [mM/s]

KCat/KM [mM/s] (protein specific)

712962

Liu

Two novel metal-independent lo ...

Geobacillus thermodenitrificans, Geobacillus thermodenitrificans NG80-2

Microbiology

155

2078-2085

2009

1

-

1

-

-

-

10

5

-

3

4

-

-

4

-

-

-

-

-

-

-

-

26

1

4

1

-

1

3

1

1

-

4

-

-

-

1

-

2

6

-

-

-

-

19

-

5

-

5

4

-

-

-

-

-

-

-

-

-

26

1

2

-

2

3

2

2

-

-

-

-

-

-

5

5

656603

Luesch

Biosynthesis of 4-methylprolin ...

Nostoc sp.

J. Org. Chem.

68

83-91

2003

-

-

1

-

-

-

-

2

-

1

1

1

-

4

-

-

1

-

-

-

-

-

4

1

1

1

-

-

-

1

-

-

1

-

-

-

-

-

1

1

-

-

-

-

-

-

2

-

1

1

1

-

-

-

1

-

-

-

-

4

1

1

-

-

-

1

-

-

-

-

-

-

-

-

-

347799

Nagashima

-

Long-chain n-alkanol dehydroge ...

Pseudomonas putida

J. Ferment. Bioeng.

82

328-333

1996

-

-

-

-

-

-

-

11

-

1

2

-

-

1

-

-

1

-

-

-

-

-

9

2

-

1

-

2

-

2

-

-

1

-

-

-

-

-

-

1

-

-

-

-

-

-

11

-

1

2

-

-

-

-

1

-

-

-

-

9

2

1

-

2

-

2

-

-

-

-

-

-

-

-

-

288324

Van Ophem

NAD-linked, factor-dependent f ...

Amycolatopsis methanolica

Eur. J. Biochem.

206

511-518

1992

-

-

-

-

-

-

5

7

-

1

2

1

-

7

-

-

-

-

-

-

-

-

7

2

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

5

-

7

-

1

2

1

-

-

-

-

-

-

-

-

7

2

-

-

-

-

-

-

-

-

-

-

-

-

-

-

347798

Ribas de Pouplana

-

Structural properties of long- ...

Equus caballus

Biochem. J.

276

433-438

1991

-

-

-

-

-

-

-

-

-

-

-

-

-

1

-

-

-

-

-

1

-

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

1

-

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

347795

Ueda

Long-chain alcohol dehydrogena ...

Candida tropicalis, Yarrowia lipolytica

Methods Enzymol.

188

171-175

1990

-

-

-

-

-

6

-

-

-

-

-

4

-

4

-

-

-

-

-

-

-

-

9

-

-

2

-

-

-

-

-

-

2

-

-

-

-

-

-

2

-

-

6

-

-

-

-

-

-

-

4

-

-

-

-

-

-

-

-

9

-

2

-

-

-

-

-

-

-

-

-

-

-

-

-

347796

Yamada

Subcellular localization of lo ...

Candida tropicalis

Arch. Microbiol.

128

145-151

1980

-

-

-

-

-

-

-

-

-

-

-

2

-

2

-

-

-

-

-

-

-

-

3

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

2

-

-

-

-

-

-

-

-

3

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

347794

Lee

Characterization of fatty alco ...

Rattus norvegicus

J. Biol. Chem.

254

2892-2896

1979

1

-

-

-

-

-

3

1

-

-

-

1

-

1

-

-

-

-

-

1

-

-

4

-

-

1

-

-

-

2

-

-

1

-

-

-

1

-

-

1

-

-

-

-

3

-

1

-

-

-

1

-

-

-

-

-

1

-

-

4

-

1

-

-

-

2

-

-

-

-

-

-

-

-

-

347800

Eklund

Three-dimensional structure of ...

Equus caballus

J. Mol. Biol.

102

27-59

1976

-

-

-

1

-

-

-

-

-

-

-

-

-

1

-

-

-

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-