Literature summary for 1.1.1.184 extracted from

Honda, K.; Ono, T.; Okano, K.; Miyake, R.; Dekishima, Y.; Kawabata, H.
Expression of engineered carbonyl reductase from Ogataea minuta in Rhodococcus opacus and its application to whole-cell bioconversion in anhydrous solvents (2019), J. Biosci. Bioeng., 127, 145-149 .

Search for more literature for 1.1.1.184

Cloned(Commentary)

Cloned (Comment)	Organism
mutant enzyme V166A is co-expressed with alcohol dehydrogenase from Thermoanaerobacter ethanolicus in Rhodococcus opacus strain B-4	Ogataea minuta

Protein Variants

Protein Variants	Comment	Organism
V166A	the mutant has increased activity with 2,2,2-trifluoroacetophenone compared to the wild type enzyme	Ogataea minuta

Organism

Organism	UniProt	Comment	Textmining
Ogataea minuta	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2,2,2-trifluoroacetophenone + NADPH + H+	-	Ogataea minuta	alpha-(trifluoromethyl)benzyl alcohol + NADP+	-	?

Subunits

Subunits	Comment	Organism
?	x * 27000, SDS-PAGE	Ogataea minuta

Synonyms

Synonyms	Comment	Organism
carbonyl reductase 1	-	Ogataea minuta
CBR1	-	Ogataea minuta
NADPH-dependent carbonyl reductase	-	Ogataea minuta

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Ogataea minuta

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Release 2023.1 (January 2023)