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Literature summary for 1.1.1.184 extracted from

  • Liang, Q.; Liu, R.; Du, S.; Ding, Y.
    Structural insights on the catalytic site protection of human carbonyl reductase 1 by glutathione (2015), J. Struct. Biol., 192, 138-144.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
in complex with glutathione, in the absence of its substrates or inhibitors. The glutathione molecule contributes to the substrate selectivity and protects the catalytic center of hCBR1 through a switch-like mechanism. Glutathione directly binds with hCBR1 when thereย’s no substrate Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P16152
-
-

Synonyms

Synonyms Comment Organism
hCBR1
-
Homo sapiens