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Literature summary for 1.1.1.184 extracted from

  • Kansal, H.; Banerjee, U.C.
    Enhancing the biocatalytic potential of carbonyl reductase of Candida viswanathii using aqueous-organic solvent system (2009), Biores. Technol., 100, 1041-1047.
    View publication on PubMed
Search for more literature for 1.1.1.184

Activating Compound

Activating Compound Comment Organism Structure
2-propanol increases conversion, giving the conversion of 90% compared to 9% in control at a substrate concentration of 70 mM in 1 h. Operational stability increases at higher temperatures with the addition of 2-propanol in the reaction mixture with good conversion (90%) and enantiomeric excess (more than 99%) at 45°C and 50°C. It may be used as a co-substrate for the bioreduction reaction, which may help in widening its applicability in terms of substrate tolerance, reduced time of conversion, increased conversion rate and thermostability Candida viswanathii
hexane activity retention is highest in the presence of hexane, reaction shows maximum conversion and enantiomeric excess of 96 and more than 99%, respectively in 15%, v/v hexane with 2-propanol as the cosubstrate Candida viswanathii
additional information for free cells, activity retention is low in ethanol, butanol and benzyl alcohol Candida viswanathii

Organism

Organism UniProt Comment Textmining
Candida viswanathii
-
-
-
Candida viswanathii MTCC 5158
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-acetonaphtone + NADPH + H+
-
 Candida viswanathii ? + NADP+
-
 ?
1-acetonaphtone + NADPH + H+
-
 Candida viswanathii MTCC 5158 ? + NADP+
-
 ?

Synonyms

Synonyms Comment Organism
carbonyl reductase
-
 Candida viswanathii