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Literature summary for 1.1.1.169 extracted from

  • Miller, C.N.; LoVullo, E.D.; Kijek, T.M.; Fuller, J.R.; Brunton, J.C.; Steele, S.P.; Taft-Benz, S.A.; Richardson, A.R.; Kawula, T.H.
    PanG, a new ketopantoate reductase involved in pantothenate synthesis (2013), J. Bacteriol., 195, 965-976.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Francisella tularensis subsp. novicida
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Synonyms

Synonyms Comment Organism
ketopantoate reductase
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Francisella tularensis subsp. novicida
KPR
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Francisella tularensis subsp. novicida
panG
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Francisella tularensis subsp. novicida

General Information

General Information Comment Organism
malfunction both the homologous gene from Enterococcus faecalis V583 (EF1861) and Escherichia coli panE functionally complement Francisella novicida lacking any KPR. Furthermore, panG from Francisella novicida can complement an Escherichia coli KPR double mutant. A panG deletion mutant is a pantothenate auxotroph and is genetically and chemically complemented with pang in trans or with the addition of pantolactone Francisella tularensis subsp. novicida