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Literature summary for 1.1.1.153 extracted from

  • Hirakawa, H.; Sawada, H.; Yamahama, Y.; Takikawa, S.; Shintaku, H.; Hara, A.; Mase, K.; Kondo, T.; Iino, T.
    Expression analysis of the aldo-keto reductases involved in the novel biosynthetic pathway of tetrahydrobiopterin in human and mouse tissues (2009), J. Biochem., 146, 51-60.
    View publication on PubMed
Search for more literature for 1.1.1.153

Inhibitors

Inhibitors Comment Organism Structure
N-acetylserotonin activity is completely inhibited by the addition of 0.5 mM N-acetylserotonin Homo sapiens
N-acetylserotonin activity is completely inhibited by the addition of 0.5 mM N-acetylserotonin Mus musculus

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Mus musculus
-
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6-pyruvoyl tetrahydropterin + NADPH + H+
-
 Mus musculus 1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADP+
-
 ?
6-pyruvoyl tetrahydropterin + NADPH + H+
-
 Homo sapiens 1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADP+
-
 ?
sepiapterin + NADPH + H+
-
 Mus musculus 7,8-dihydrobiopterin + NADP+
-
 ?
sepiapterin + NADPH + H+
-
 Homo sapiens 7,8-dihydrobiopterin + NADP+
-
 ?

Synonyms

Synonyms Comment Organism
AKR1B1
-
 Mus musculus
SPR
-
 Mus musculus
SPR
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Mus musculus
NADPH
-
 Homo sapiens