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Literature summary for 1.1.1.153 extracted from

  • Choi, Y.K.; Kong, J.S.; Park, Y.S.
    Functional role of sepiapterin reductase in the biosynthesis of tetrahydropteridines in Dictyostelium discoideum Ax2 (2006), Biochim. Biophys. Acta, 1760, 877-882.
    View publication on PubMed
Search for more literature for 1.1.1.153

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1'-oxo-2'-D-hydroxypropyl-tetrahydropterin + NADPH Dictyostelium discoideum
-
 tetrahydrodictyopterin + NADP+
-
 ?
1'-oxo-2'-D-hydroxypropyl-tetrahydropterin + NADPH Dictyostelium discoideum AX2
-
 tetrahydrodictyopterin + NADP+
-
 ?
1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADPH Dictyostelium discoideum
-
 L-erythro-tetrahydrobiopterin + NADP+
-
 ?
1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADPH Dictyostelium discoideum AX2
-
 L-erythro-tetrahydrobiopterin + NADP+
-
 ?
6-pyruvoyltetrahydropterin + NADPH Dictyostelium discoideum
-
 1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADP+ no synthesis of the D-isomer ?
6-pyruvoyltetrahydropterin + NADPH Dictyostelium discoideum AX2
-
 1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADP+ no synthesis of the D-isomer ?
additional information Dictyostelium discoideum quantitative in vivo assay and product determination ?
-
 ?
additional information Dictyostelium discoideum AX2 quantitative in vivo assay and product determination ?
-
 ?

Organism

Organism UniProt Comment Textmining
Dictyostelium discoideum
-
-
-
Dictyostelium discoideum AX2
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information SR gene expression and activity in different developmental stages Dictyostelium discoideum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1'-oxo-2'-D-hydroxypropyl-tetrahydropterin + NADPH
-
 Dictyostelium discoideum tetrahydrodictyopterin + NADP+
-
 ?
1'-oxo-2'-D-hydroxypropyl-tetrahydropterin + NADPH preferred substrate Dictyostelium discoideum tetrahydrodictyopterin + NADP+
-
 ?
1'-oxo-2'-D-hydroxypropyl-tetrahydropterin + NADPH
-
 Dictyostelium discoideum AX2 tetrahydrodictyopterin + NADP+
-
 ?
1'-oxo-2'-D-hydroxypropyl-tetrahydropterin + NADPH preferred substrate Dictyostelium discoideum AX2 tetrahydrodictyopterin + NADP+
-
 ?
1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADPH
-
 Dictyostelium discoideum L-erythro-tetrahydrobiopterin + NADP+
-
 ?
1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADPH
-
 Dictyostelium discoideum AX2 L-erythro-tetrahydrobiopterin + NADP+
-
 ?
6-pyruvoyltetrahydropterin + NADPH
-
 Dictyostelium discoideum 1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADP+ no synthesis of the D-isomer ?
6-pyruvoyltetrahydropterin + NADPH
-
 Dictyostelium discoideum AX2 1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADP+ no synthesis of the D-isomer ?
additional information quantitative in vivo assay and product determination Dictyostelium discoideum ?
-
 ?
additional information product determination Dictyostelium discoideum ?
-
 ?
additional information quantitative in vivo assay and product determination Dictyostelium discoideum AX2 ?
-
 ?

Synonyms

Synonyms Comment Organism
SR
-
 Dictyostelium discoideum

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
22
-
 assay at Dictyostelium discoideum

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
 assay at Dictyostelium discoideum

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Dictyostelium discoideum