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Literature summary for 1.1.1.153 extracted from

  • Fujimoto, K.; Sakurai, M.; Kawase, M.; Katoh, S.
    Effect of antisense oligodeoxynucleotide for sepiapterin reductase on the viability of PC12 cells in the presence of exogenous carbonyl compounds (2003), Chem. Biol. Interact., 143-144, 583-586.
    View publication on PubMed
Search for more literature for 1.1.1.153

Cloned(Commentary)

Cloned (Comment) Organism
host cells transfected with sense, antisense and inverse antisense oligodeoxynucleotides Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
N-acetylserotonin
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6-pyruvoyl tetrahydropterin + 2 NADPH + 2 H+ Rattus norvegicus final step in the synthesis of tetrahydrobiopterin, role in detoxification of exogenous carbonyl compounds suggested tetrahydrobiopterin + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
PC-12 cell cell culture model for catecholaminergic neurons Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-phenyl-1,2-propanedione + NADPH
-
 Rattus norvegicus ?
-
 ?
6-pyruvoyl tetrahydropterin + 2 NADPH + 2 H+ final step in the synthesis of tetrahydrobiopterin, role in detoxification of exogenous carbonyl compounds suggested Rattus norvegicus tetrahydrobiopterin + NADP+
-
 ?

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Rattus norvegicus