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Literature summary for 1.1.1.149 extracted from

  • Choi, J.H.; Ishida, M.; Matsuwaki, T.; Yamanouchi, K.; Nishihara, M.
    Involvement of 20alpha-hydroxysteroid dehydrogenase in the maintenance of pregnancy in mice (2008), J. Reprod. Dev., 54, 408-412.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
progesterone + NAD(P)H + H+ Mus musculus maternal and fetal 20alpha-HSD play a role in maintaining normal pregnancy at least partially by reducing progesterone concentrations in fetuses 20alpha-hydroxyprogesterone + NAD(P)+
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
fetus
-
 Mus musculus
-
ovary
-
 Mus musculus
-
placenta
-
 Mus musculus
-
uterus
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
progesterone + NAD(P)H + H+ maternal and fetal 20alpha-HSD play a role in maintaining normal pregnancy at least partially by reducing progesterone concentrations in fetuses Mus musculus 20alpha-hydroxyprogesterone + NAD(P)+
-
 ?

Synonyms

Synonyms Comment Organism
20alpha-HSD
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
NAD(P)+
-
 Mus musculus