Inhibitors | Comment | Organism | Structure |
---|---|---|---|
glycyrrhetinic acid | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cortisone + NADPH + H+ | Homo sapiens | biological transformation of inactive cortisone to active cortisol | cortisol + NADP+ | - |
? | |
additional information | Homo sapiens | isozyme 11beta-HSD1-driven cortisone reactivation regulates plasminogen activator inhibitor type 1, PAI-1, in adipose tissue of obese women | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
obese women | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipose tissue | expression of isozyme 11beta-HSD1, in situ hybridization, overview | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cortisone + NADPH + H+ | - |
Homo sapiens | cortisol + NADP+ | - |
? | |
cortisone + NADPH + H+ | biological transformation of inactive cortisone to active cortisol | Homo sapiens | cortisol + NADP+ | - |
? | |
additional information | isozyme 11beta-HSD1-driven cortisone reactivation regulates plasminogen activator inhibitor type 1, PAI-1, in adipose tissue of obese women | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
11beta-HSD1 | - |
Homo sapiens |
11beta-hydroxysteroid dehydrogenase type 1 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Homo sapiens |