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Literature summary for 1.1.1.145 extracted from

  • Hebert, P.; Cooke, G.M.
    Kinetic evidence for separate 3beta-hydroxysteroid dehydrogenase-isomerases in androgen and 16-androstene biosynthetic pathways in the pig testis (1992), J. Steroid Biochem. Mol. Biol., 42, 901-910.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Sus scrofa
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dehydroepiandrosterone + NAD+ Sus scrofa
-
androst-5-en-3,17-dione + NADH + H+
-
?
pregnenolone + NAD(P)+ Sus scrofa
-
pregn-5-en-3,20-dione + NAD(P)H + H+
-
?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
testis
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3beta,17alpha-dihydroxy-5-pregnen-20-one + NAD(P)+
-
Sus scrofa 17alpha-hydroxypregn-5-ene-3,20-dione + NAD(P)H
-
?
5,16-androstadien-3beta-ol + NAD+
-
Sus scrofa 5,16-androstadien-3-one + NADH
-
?
dehydroepiandrosterone + NAD+
-
Sus scrofa androst-5-en-3,17-dione + NADH + H+
-
?
pregnenolone + NAD(P)+
-
Sus scrofa pregn-5-en-3,20-dione + NAD(P)H + H+
-
?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Sus scrofa