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Literature summary for 1.1.1.133 extracted from

  • Nakano, Y.; Suzuki, N.; Yoshida, Y.; Nezu, T.; Yamashita, Y.; Koga, T.
    Thymidine diphosphate-6-deoxy-L-lyxo-4-hexulose reductase synthesizing dTDP-6-deoxy-L-talose from Actinobacillus actinomycetemcomitans (2000), J. Biol. Chem., 275, 6806-6812.
    View publication on PubMed
Search for more literature for 1.1.1.133

Cloned(Commentary)

Cloned (Comment) Organism
overexpression in Escherichia coli DH5alpha, ER2566, BL21(DE3) Aggregatibacter actinomycetemcomitans

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
31900
-
 Y4 rmlD gene product, SDS-PAGE Aggregatibacter actinomycetemcomitans
32400
-
 NCTC 9710 rmlD gene product, SDS-PAGE Aggregatibacter actinomycetemcomitans

Organism

Organism UniProt Comment Textmining
Aggregatibacter actinomycetemcomitans
-
 Y4, NCTC 9710
-
Escherichia coli
-
 O45
-
Escherichia coli O45
-
 O45
-

Purification (Commentary)

Purification (Comment) Organism
chromatography Aggregatibacter actinomycetemcomitans

Storage Stability

Storage Stability Organism
-20°C, purified protein, 50% glycerol Aggregatibacter actinomycetemcomitans

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dTDP-6-deoxy-L-lyxo-4-hexulose + NADPH
-
 Aggregatibacter actinomycetemcomitans dTDP-L-rhamnose + NADP+
-
 ?
dTDP-6-deoxy-L-lyxo-4-hexulose + NADPH
-
 Aggregatibacter actinomycetemcomitans NCTC 9710 dTDP-L-rhamnose + NADP+
-
 ?

Synonyms

Synonyms Comment Organism
dTDP-6-deoxy-L-lyxo-4-hexulose reductase
-
 Aggregatibacter actinomycetemcomitans
thymidine diphosphate-6-deoxy-L-talose
-
 Aggregatibacter actinomycetemcomitans

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Escherichia coli
NADPH
-
 Aggregatibacter actinomycetemcomitans