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Literature summary for 1.1.1.103 extracted from

  • Le Floch, N.; Seve, B.
    Catabolism through the threonine dehydrogenase pathway does not account for the high first-pass extraction rate of dietary threonine by the portal drained viscera in pigs (2005), Br. J. Nutr., 93, 447-456.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-threonine + NAD+ Sus scrofa catabolism through the threonine dehydrogenase pathway does not account for the high first-pass extraction rate of dietary threonine by the portal drained viscera in pigs, overview (2S)-2-amino-3-oxobutanoate + NADH + H+
-
?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Sus scrofa
-
additional information no activity in intestine Sus scrofa
-
pancreas
-
Sus scrofa
-
splanchnic tissue extensive threonine utilization Sus scrofa
-
viscus portal drained viscera, PDV Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
threonine sequestration in the portal drained viscera and liver, threonine flux, overview Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-threonine + NAD+
-
Sus scrofa (2S)-2-amino-3-oxobutanoate + NADH + H+
-
?
L-threonine + NAD+ catabolism through the threonine dehydrogenase pathway does not account for the high first-pass extraction rate of dietary threonine by the portal drained viscera in pigs, overview Sus scrofa (2S)-2-amino-3-oxobutanoate + NADH + H+
-
?

Synonyms

Synonyms Comment Organism
threonine dehydrogenase
-
Sus scrofa

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Sus scrofa