Activating Compound | Comment | Organism | Structure |
---|---|---|---|
dihydroxyacetone | activation, used as carbon source in wild type cell cultures, greater activity compared to activity in glucose-grown cells | Saccharomyces cerevisiae | |
ethanol | activation, used as nonfermentable carbon source in wild type and tpa1 mutant cell cultures, greater activity compared to activity in glucose-grown cells | Saccharomyces cerevisiae | |
glycerol | activation, used as nonfermentable carbon source in wild type cell cultures, greater activity compared to activity in glucose-grown cells | Saccharomyces cerevisiae | |
glycerol/ethanol | activation, used as nonfermentable carbon source in wild type cell cultures, greater activity compared to activity in glucose-grown cells | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyldihydroxyacetone phosphate + NADPH | Saccharomyces cerevisiae | acyldihydroxyacetone phosphate pathway | 1-acyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
acyldihydroxyacetone phosphate + NADPH | Saccharomyces cerevisiae | reaction in non-ether lipids biosynthesis | 1-acyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
acyldihydroxyacetone phosphate + NADPH | Saccharomyces cerevisiae tpa1 | acyldihydroxyacetone phosphate pathway | 1-acyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
acyldihydroxyacetone phosphate + NADPH | Saccharomyces cerevisiae tpa1 | reaction in non-ether lipids biosynthesis | 1-acyl-sn-glycerol 3-phosphate + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
tpa1 mutant strain | - |
Saccharomyces cerevisiae | - |
wild-type strain | - |
Saccharomyces cerevisiae tpa1 | - |
tpa1 mutant strain | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.00393 | - |
glucose grown cells | Saccharomyces cerevisiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyldihydroxyacetone phosphate + NADPH | - |
Saccharomyces cerevisiae | 1-acyl-sn-glycerol 3-phosphate + NADP+ | i.e. lysophosphatidic acid | ? | |
acyldihydroxyacetone phosphate + NADPH | acyldihydroxyacetone phosphate pathway | Saccharomyces cerevisiae | 1-acyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
acyldihydroxyacetone phosphate + NADPH | reaction in non-ether lipids biosynthesis | Saccharomyces cerevisiae | 1-acyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
acyldihydroxyacetone phosphate + NADPH | - |
Saccharomyces cerevisiae tpa1 | 1-acyl-sn-glycerol 3-phosphate + NADP+ | i.e. lysophosphatidic acid | ? | |
acyldihydroxyacetone phosphate + NADPH | acyldihydroxyacetone phosphate pathway | Saccharomyces cerevisiae tpa1 | 1-acyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
acyldihydroxyacetone phosphate + NADPH | reaction in non-ether lipids biosynthesis | Saccharomyces cerevisiae tpa1 | 1-acyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
hexadecyldihydroxyacetone phosphate + NADPH | - |
Saccharomyces cerevisiae | 1-hexadecyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
hexadecyldihydroxyacetone phosphate + NADPH | - |
Saccharomyces cerevisiae tpa1 | 1-hexadecyl-sn-glycerol 3-phosphate + NADP+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | hydrogen from B-side of nicotinamide ring is transferred to reduce keto substrates | Saccharomyces cerevisiae |