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Literature summary for 1.1.1.1 extracted from

  • Avila, E.E.; Martinez-Alcaraz, E.R.; Barbosa-Sabanero, G.; Rivera-Baron, E.I.; Arias-Negrete, S.; Zazueta-Sandoval, R.
    Subcellular localization of the NAD+-dependent alcohol dehydrogenase in Entamoeba histolytica trophozoites (2002), J. Parasitol., 88, 217-222.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol enzyme polymer forms rod-like helical particles Entamoeba histolytica 5829
-
additional information detection in the membrane pellet is probably due to cosedimentation of the multimeric enzyme during membrane purification Entamoeba histolytica
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
96000
-
x * 96000, SDS-PAGE Entamoeba histolytica

Organism

Organism UniProt Comment Textmining
Entamoeba histolytica
-
-
-
Entamoeba histolytica HM1
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial by isopycnic sucrose gradient centrifugation Entamoeba histolytica

Source Tissue

Source Tissue Comment Organism Textmining
trophozoite
-
Entamoeba histolytica
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.092
-
partially purified enzyme Entamoeba histolytica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ethanol + NAD+
-
Entamoeba histolytica acetaldehyde + NADH
-
?
ethanol + NAD+
-
Entamoeba histolytica HM1 acetaldehyde + NADH
-
?

Subunits

Subunits Comment Organism
? x * 96000, SDS-PAGE Entamoeba histolytica

Synonyms

Synonyms Comment Organism
ADH2
-
Entamoeba histolytica

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
22
-
assay at room temperature Entamoeba histolytica

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
9.5
-
assay at Entamoeba histolytica

Cofactor

Cofactor Comment Organism Structure
NAD+ dependent on Entamoeba histolytica