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Literature summary for 1.1.1.1 extracted from
- Partial purification and properties of alcohol dehydrogenase from unicellular green alga Chlamydomonas moewusii (1983), Phytochemistry, 22, 1695-1699.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,10-phenanthroline | - |
Chlamydomonas moewusii |  |
| iodoacetamide | - |
Chlamydomonas moewusii | |
| NaN3 | - |
Chlamydomonas moewusii | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.11 | - |
NADH | - |
Chlamydomonas moewusii | |
| 0.125 | - |
NAD+ | - |
Chlamydomonas moewusii | |
| 1.25 | - |
acetaldehyde | - |
Chlamydomonas moewusii | |
| 22.2 | - |
ethanol | - |
Chlamydomonas moewusii | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zinc | contains 4 zinc atoms per dimer | Chlamydomonas moewusii | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 42000 | - |
2 * 42000, SDS-PAGE | Chlamydomonas moewusii |
| 94000 | - |
gel filtration | Chlamydomonas moewusii |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Chlamydomonas moewusii | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Chlamydomonas moewusii |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| a primary alcohol + NAD+ = an aldehyde + NADH + H+ | Theorell-Chance mechanism | Chlamydomonas moewusii |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Chlamydomonas moewusii |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ethanol + NAD+ | - |
Chlamydomonas moewusii | acetaldehyde + NADH | - |
? | |
| pentanol + NAD+ | - |
Chlamydomonas moewusii | n-pentanal + NADH | - |
? | |
| propan-1,2-diol + NAD+ | - |
Chlamydomonas moewusii | ? + NADH | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 42000, SDS-PAGE | Chlamydomonas moewusii |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.8 | - |
oxidation of NADH | Chlamydomonas moewusii |
| 9.1 | - |
reduction of NAD+ | Chlamydomonas moewusii |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Chlamydomonas moewusii | |
| NADH | - |
Chlamydomonas moewusii | |
| NADP+ | no activity as coenzyme | Chlamydomonas moewusii | |
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