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dabsyl-L-methionine (S)-S-oxide + dithiothreitol = dabsyl-L-methionine + dithiothreitol disulfide + H2O
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dabsyl-L-methionine-(S)-S-oxide + dithiothreitol = dabsyl-L-methionine + dithiothreitol disulfide + H2O
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dabsyl-L-methionine-(S)-S-oxide + dithiothreitol = dabsyl-L-methionine + DTT disulfide + H2O
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dabsyl-L-methionine-(S)-S-oxide + DTT = dabsyl-L-methionine + DTT disulfide + H2O
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dabsyl-L-methionine-(S)-S-oxide + thioredoxin = dabsyl-L-methionine + thioredoxin disulfide + H2O
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0.026
-
isolated MrsA domain, pH 7.5, 37°C
0.045
-
mutant Y163A//E165A, pH 7.5, 37°C
0.068
-
mutant Y163A, pH 7.5, 37°C
0.096
-
mutant E165A, pH 7.5, 37°C
0.108
-
mutant C285S, pH 7.5, 37°C
0.11
-
mutant D164A, pH 7.5, 37°C
0.12
-
wild-type, pH 7.5, 37°C
0.28
-
recombinant wild-type MsrA, with DTT, pH 7.5, 37°C
0.78
-
recombinant truncated MsrA DELTA(1-46), with DTT, pH 7.5, 37°C
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0.14
-
mutant D164A, pH 7.5, 37°C
0.15
-
mutant E165A, pH 7.5, 37°C
0.17
-
mutant Y163A, pH 7.5, 37°C
0.18
-
wild-type, pH 7.5, 37°C
0.3
-
isolated MrsA domain, pH 7.5, 37°C
0.3
-
mutant C285S, pH 7.5, 37°C
0.34
-
recombinant wild-type MsrA, with DTT, pH 7.5, 37°C
1.03
-
mutant Y163A//E165A, pH 7.5, 37°C
4.3
-
recombinant truncated MsrA DELTA(1-46), with DTT, pH 7.5, 37°C
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Methionine sulfoxide reductase (MsrA) is a regulator of antioxidant defense and lifespan in mammals
2001
Moskovitz, J.; Bar-Noy, S.; Williams, W.M.; Requena, J.; Berlett, B.S.; Stadtman, E.R.
Proc. Natl. Acad. Sci. USA
98
12920-12925
Role of structural and functional elements of mouse methionine-S-sulfoxide reductase in its subcellular distribution
2005
Kim, H.Y.; Gladyshev, V.N.
Biochemistry
44
8059-8067
The yeast cytosolic thioredoxins are involved in the regulation of methionine sulfoxide reductase A
2006
Hanbauer, I.; Moskovitz, J.
Free Radic. Biol. Med.
40
1391-1396
Peptide methionine sulfoxide reductase (MsrA) is not a major virulence determinant for the oral pathogen Actinobacillus actinomycetemcomitans
2002
Mintz, K.P.; Moskovitz, J.; Wu, H.; Fives-Taylor, P.M.
Microbiology
148
3695-3703
Overexpression of peptide-methionine sulfoxide reductase in Saccharomyces cerevisiae and human T cells provides them with high resistance to oxidative stress
1998
Moskovitz, J.; Flescher, E.; Berlett, B.S.; Azare, J.; Poston, J.M.; Stadtman, E.R.
Proc. Natl. Acad. Sci. USA
95
14071-14075
Thioredoxin as a reducing agent for mammalian methionine sulfoxide reductases B lacking resolving cysteine
2008
Kim, H.Y.; Kim, J.R.
Biochem. Biophys. Res. Commun.
371
490-494
Methionine sulfoxide reductase from the hyperthermophilic archaeon Thermococcus kodakaraensis, an enzyme designed to function at suboptimal growth temperatures
2007
Fukushima, E.; Shinka, Y.; Fukui, T.; Atomi, H.; Imanaka, T.
J. Bacteriol.
189
7134-7144
Essential role of the linker region in the higher catalytic efficiency of a bifunctional MsrA-MsrB fusion protein
2016
Han, A.R.; Kim, M.J.; Kwak, G.H.; Son, J.; Hwang, K.Y.; Kim, H.Y.
Biochemistry
55
5117-5127