Ligand 4-nitroaniline

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Basic Ligand Information

Molecular Structure
Picture of 4-nitroaniline (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H6N2O2
4-nitroaniline
WKDURMTZOWGWTD-UHFFFAOYSA-L
Synonyms:
4-aminonitrobenzene, 4-nitroanilide, 4-nitrolaniline, 4-nitronaniline, 4-nitrophenylamine, p-nitoaniline, p-nitroaniline, p-pitroaniline, para-nitroaniline, PNA

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-Glu-4-nitroanilide + glutathione = 4-nitroaniline + 5-L-glutamyl-glutathione
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Nalpha-benzoyl-DL-arginine-4-nitroanilide + H2O = Nalpha-benzoyl-DL-arginine + 4-nitroaniline
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butyloxycarbonyl-L-Gln-L-Ala-L-Arg-4-nitroanilide + H2O = butyloxycarbonyl-L-Gln-L-Ala-L-Arg + 4-nitroaniline
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D-Leu-Phg-Arg-4-nitroanilide + H2O = D-Leu-Phg-Arg + 4-nitroaniline
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methoxysuccinyl-Ala-Ala-Pro-Val-4-nitroanilide + H2O = methoxysuccinyl-Ala-Ala-Pro-Val + 4-nitroanilide
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Z-Leu-Leu-Glu-NH-4-nitroanilide + H2O = Z-Leu-Leu-Glu + 4-nitroaniline
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4-nitroacetanilide + H2O = acetate + 4-nitroaniline
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4-nitrophenyl-3-ketovalidamine = 4-nitroaniline + 5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one
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Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-nitroaniline + NADH + H+ = ? + NAD+
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malonyl-CoA + 4-nitroaniline = CoA + N-(4-nitrophenyl)-malonamate
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Product in Enzyme-catalyzed Reactions (1893 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5'-phospho-pyridoxyl-4-aminonitrobenzene + H2O + O2 = pyridoxal 5'-phosphate + 4-aminonitrobenzene + H2O2
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1-(4'-nitrophenylazo)-2-hydroxy-6-sulfonaphthalene + NAD(P)H = 4-nitrophenylamine + NAD(P)+ + 1-amino-2-hydroxy-6-sulfonaphthalene
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p-nitroacetanilide + aniline = p-nitroaniline + acetanilide
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gamma-glutamyl-p-nitroanilide + H2O = L-glutamate + p-nitroaniline
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L-gamma-glutamyl-p-nitroanilide + H2O = L-glutamine + p-nitroaniline
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L-gamma-glutamine-4-nitroanilide + H2O = L-glutamate + 4-nitroaniline
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Leu-4-nitroanilide + H2O = Leu + 4-nitroaniline
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L-Asp-4-nitroanilide + H2O = L-Asp + 4-nitroaniline
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S-benzyl-L-Cys-4-nitroanilide + H2O = S-benzyl-L-Cys + 4-nitroaniline
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Gly-Pro-p-nitroanilide + H2O = Gly + Pro + p-nitroaniline
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Suc-Ala-Ala-Pro-Phe-4-nitroanilide + H2O = Suc-Ala-Ala-Pro-Phe + 4-nitroaniline
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Nalpha-benzoyl-Ile-Glu(-OR)-Gly-Arg-4-nitroanilide + H2O = Nalpha-benzoyl-Ile-Glu(-OR)-Gly-Arg + 4-nitroaniline
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Ac-Lys-Arg-4-nitroanilide + H2O = Ac-Lys-Arg + 4-nitroaniline
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benzoyl-Arg 4-nitroanilide + H2O = benzoyl-Arg + 4-nitroaniline
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benzoyl-Ile-Glu-Gly-Arg 4-nitroanilide + H2O = benzoyl-Ile-Glu-Gly-Arg + 4-nitroaniline
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N-succinyl-Ala-Ala-Pro-Phe-4-nitroanilide + H2O = N-succinyl-Ala-Ala-Pro-Phe + 4-nitroaniline
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Succinyl-tri-L-alanine 4-nitroanilide + H2O = Succinyl-tri-L-alanine + 4-nitroaniline
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