Ligand pyruvate kinase

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Basic Ligand Information

Molecular Structure
Picture of pyruvate kinase (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C42H66N10O8R2
pyruvate kinase
LRUPROVAHFMXQZ-JDQHVGNYSA-N
Synonyms:
[pyruvate kinase]

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
phosphopyruvate kinase + H2O = pyruvate kinase + phosphate
show the reaction diagram
-
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[pyruvate kinase] phosphate + H2O = pyruvate kinase + phosphate
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + pyruvate kinase = ADP + phosphorylated pyruvate kinase
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ATP + pyruvate kinase = ADP + phospho-[pyruvate kinase]
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
reduced pyruvate kinase + O2 = pyruvate kinase + H2O
show the reaction diagram
-
-
phosphopyruvate kinase + H2O = pyruvate kinase + phosphate
show the reaction diagram
-
-
[pyruvate kinase] phosphate + H2O = pyruvate kinase + phosphate
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
builds complex with Pra with specific GTP synthesis activity
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Enzyme Kinetic Parameters

References & Links

Links to other databases for pyruvate kinase

ChEBI
PubChem
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PubChem