Ligand Arachidonoyl-CoA

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of Arachidonoyl-CoA (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C41H66N7O17P3S
Arachidonoyl-CoA
JDEPVTUUCBFJIW-YQVDHACTSA-N
Synonyms:
(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA, 5,8,11,14-eicosatetraenoyl-CoA, arachidonoyl-coenzyme A, arachidonyl-CoA

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
arachidonoyl-CoA + NADPH + H+ = arachidonic aldehyde + CoA + NADP+
show the reaction diagram
-
arachidonoyl-CoA + dolichol = CoA + dolichyl arachidonate
show the reaction diagram
-
arachidonoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine = CoA + 1-alkenyl-2-arachidonoyl-glycero-3-phosphorylcholine
show the reaction diagram
-
arachidonoyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1-acyl-2-arachidonoyl-sn-glycerol 3-phosphate
show the reaction diagram
-
arachidonoyl-CoA + 1-acyl-lysophosphatidylinositol = CoA + 1-acyl-2-arachidonoyl-lysophosphatidylinositol
show the reaction diagram
-
arachidonoyl-CoA + H2O = CoA + arachidonate
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(8Z,11Z,14Z)-icosa-8,11,14-trienoyl-CoA + ferrocytochrome b5 + O2 + H+ = arachidonoyl-CoA + ferricytochrome b5 + H2O
show the reaction diagram
-
-
ATP + arachidonate + CoA = AMP + diphosphate + arachidonoyl-CoA
show the reaction diagram
-
-
ATP + arachidonate + CoA = AMP + diphosphate + arachidonoyl-CoA
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (70 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5,8,11,14-eicosatetraenoyl-CoA + reduced acceptor + O2 = 5,8,11,14,17-eicosadecapentaenoyl-CoA + acceptor + H2O
show the reaction diagram
-
arachidonoyl-CoA + NADPH + H+ = arachidonic aldehyde + CoA + NADP+
show the reaction diagram
-
arachidonoyl-CoA + NADPH + H+ = (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenal + CoA + NADP+
show the reaction diagram
-
arachidonoyl-CoA + NADPH = cis-5,8,11,14-eicosatetraenal + NADP+ + CoA
show the reaction diagram
-
arachidonoyl-CoA + oxidized electron transfer flavoprotein = ? + reduced electron transfer flavoprotein
show the reaction diagram
-
arachidonoyl-CoA + 1-alkenylglycerophosphoethanolamine = CoA + 1-alkenyl-2-arachidonoylglycerophosphoethanolamine
show the reaction diagram
-
arachidonoyl-CoA + dolichol = CoA + dolichyl arachidonate
show the reaction diagram
-
arachidonoyl-CoA + glycine = CoA + N-arachidonoylglycine
show the reaction diagram
-
arachidonoyl-CoA + sn-glycerol 3-phosphate = CoA + 1-arachidonoyl-sn-glycerol 3-phosphate
show the reaction diagram
-
arachidonoyl-CoA + sn-2-monooleoylglycerol = CoA + 1-arachidonoyl-2-oleoylglycerol
show the reaction diagram
-
arachidonoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine = CoA + 1-alkenyl-2-arachidonoyl-glycero-3-phosphorylcholine
show the reaction diagram
-
arachidonoyl-CoA + 2-acyl-sn-glycerol 3-phosphate = CoA + 1-arachidonoyl-2-acyl-sn-glycerol 3-phosphate
show the reaction diagram
-
arachidonoyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine = CoA + 2-arachidonoyl-1-alkyl-sn-glycero-3-phosphocholine
show the reaction diagram
-
arachidonoyl-CoA + octopamine = CoA + N-arachidonoyloctopamine
show the reaction diagram
-
arachidonoyl-CoA + 1-acyl-lysophosphatidylinositol = CoA + 1-acyl-2-arachidonoyl-lysophosphatidylinositol
show the reaction diagram
-
arachidonoyl-CoA + H2O = CoA + arachidonate
show the reaction diagram
-
arachidonyl-CoA + H2O = arachidonate + CoA
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + arachidonate + CoA = AMP + diphosphate + arachidonoyl-CoA
show the reaction diagram
-
ATP + arachidonic acid + CoA = AMP + diphosphate + arachidonoyl-CoA
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
high concentration
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (8 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.043
-
pH 8.0, temperature not specified in the publication

KM Value (26 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0019
-
pH 8.0, temperature not specified in the publication

References & Links

Links to other databases for Arachidonoyl-CoA

ChEBI
PubChem
-
PubChem