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Ligand 2-phenylpropan-2-ol

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

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Show Natural Product (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

5.3.99.2

cumene hydroperoxide + 2 GSH = cumene hydroxide + GSSG + H2O

649720

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Product in Enzyme-catalyzed Reactions (25 results)

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Show Product (25 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.11.1.11

L-ascorbic acid + cumene hydroperoxide = dehydroascorbate + 1,1-dimethylbenzylalcohol + H2O

439858, 0, 439867

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1.11.1.11

p-cresol + cumene-hydroperoxide = 4a,9b-dihydro-8,9b-dimethyl-3(4H)-dibenzofuranone + 2,2'-dihydroxy-5,5'-dimethylbiphenyl + 1,1-dimethylbenzylalcohol + bis-(1-methyl-1-phenylethyl)peroxide

439877

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1.11.1.11

2 entries

1.11.1.20

thioredoxin + cumene hydroperoxide = thioredoxin disulfide + H2O + 2-phenylpropan-2-ol

0

-

1.11.1.24

2 thioredoxin + cumene hydroperoxide = thioredoxin disulfide + H2O + 2-phenylpropan-2-ol

0

-

1.11.1.24

cumene hydroperoxide + dithiothreitol = 2-phenylpropan-2-ol + oxidized dithiothreitol

0

-

1.11.1.24

cumene hydroperoxide + reduced dithiothreitol = 2-phenylpropan-2-ol + oxidized dithiothreitol

0

-

1.11.1.24

cumene hydroperoxide + reduced thioredoxin = 2-phenylpropan-2-ol + oxidized thioredoxin + H2O

0

-

1.11.1.24

cumene hydroperoxide + tryparedoxin 2 = 2-phenylpropan-2-ol + oxidized tryparedoxin 2

0

-

1.11.1.24

thioredoxin + cumene hydroperoxide = thioredoxin disulfide + H2O + cumene hydroxide

0

-

1.11.1.24

thioredoxin A + cumene hydroperoxide = thioredoxin A disulfide + H2O + cumene hydroxide

0

-

1.11.1.24

7 entries

1.11.1.25

cumene hydroperoxide + reduced glutaredoxin = 2-phenylpropan-2-ol + oxidized glutaredoxin

0

-

1.11.1.27

cumene hydroperoxide + GSH = 2-phenylpropan-2-ol + GSSG

0

-

1.11.1.28

cumene hydroperoxide + dihydrolipoamide = 2-phenylpropan-2-ol + lipoamide

0

-

1.11.1.28

cumene hydroperoxide + dithiothreitol = 2-phenylpropan-2-ol + oxidized dithiothreitol

0

-

1.11.1.28

a [lipoyl-carrier protein]-N6-[(R)-dihydrolipoyl]-L-lysine + cumene hydroperoxide = a [lipoyl-carrier protein]-N6-lipoyl-L-lysine + H2O + cumene hydroxide

0

-

1.11.1.28

3 entries

1.11.1.7

reduced thioredoxin 1 + cumene hydroperoxide = oxidized thioredoxin 1 + cumene hydroxide

0

-

1.11.1.9

2 glutathione + cumene hydroperoxide = glutathione disulfide + 2-phenylpropan-2-ol + H2O

0

-

1.11.1.9

cumene hydroperoxide + 2 2-nitro-5-sulfanylbenzoic acid = 2-phenylpropan-2-ol + 3,3'-disulfanediylbis(6-nitrobenzoic acid) + H2O

0

-

1.11.1.9

cumene hydroperoxide + 2 4-nitrobenzenethiol = 2-phenylpropan-2-ol + 1,1'-disulfanediylbis(4-nitrobenzene) + H2O

0

-

1.11.1.9

cumene hydroperoxide + 2 GSH = 2-phenylpropan-2-ol + GSSG + H2O

0

-

1.11.1.9

cumene hydroperoxide + 2-nitro-5-sulfanylbenzoic acid = 2-phenylpropan-2-ol + 3,3'-disulfanediylbis(6-nitrobenzoic acid) + H2O

0

-

1.11.1.9

cumene hydroperoxide + GSH = 2-phenylpropan-2-ol + GSSG + H2O

0

-

5.3.99.2

cumene hydroperoxide + 2 GSH = cumene hydroxide + GSSG + H2O

649720

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5.3.99.2

cumene hydroperoxide = cumene hydroxide

649654

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1.11.1.9

6 entries

5.3.99.2

2 entries

5.3.99.3

cumene hydroperoxide + 2 GSH = cumene hydroxide + GSSG + H2O

652399

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Enzyme Kinetic Parameters

References & Links

Literature References (6)

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Show Reference (6 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

439858

6772104

Purification and some properties of L-ascorbic-acid-specific peroxidase in Euglena gracilis Z

1980

Shigeoka, S.; Nahana, Y.; Kitaoka, S.

Arch. Biochem. Biophys.

201

121-127

439867

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Ascorbate peroxidase: a novel antioxidant enzyme in insects

1997

Mathews, M.C.; Summers, C.B.; Felton, G.W.

Arch. Insect Biochem. Physiol.

34

57-68

439877

11356136

Engineering the active site of ascorbate peroxidase

2001

Lloyd Raven, E.; Celik, A.; Cullis, P.M.; Sangar, R.; Sutcliffe, M.J.

Biochem. Soc. Trans.

29

105-111

649654

-

Sequence, catalytic properties and expression of chicken glutathione-dependent prostaglandin D2 synthase, a novel class sigma glutathione S-transferase

1998

Thomson, A.M.; Meyer, D.J.; Hayes, J.D.

Biochem. J.

333

317-325

649720

11672424

Mammalian class Sigma glutathione S-transferases: catalytic properties and tissue-specific expression of human and rat GSH-dependent prostaglandin D2 synthases

2001

Jowsey, I.R.; Thomson, A.M.; Flanagan, J.U.; Murdock, P.R.; Moore, G.B.T.; Meyer, D.J.; Murphy, G.J.; Smith, S.A.; Hayes, J.D.

Biochem. J.

359

507-516

652399

12672824

Human microsomal prostaglandin E synthase-1: purification, functional characterization, and projection structure determination

2003

Thoren, S.; Weinander, R.; Saha, S.; Jegerschoeld, C.; Pettersson, P.L.; Samuelsson, B.; Hebert, H.; Hamberg, M.; Morgenstern, R.; Jakobsson, P.J.

J. Biol. Chem.

278

22199-22209

Links to other databases for 2-phenylpropan-2-ol

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Show Links (1 entry)

ChEBI

PubChem