Ligand N-(carboxymethyl)-D-alanine

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Basic Ligand Information

Molecular Structure
Picture of N-(carboxymethyl)-D-alanine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H9NO4
N-(carboxymethyl)-D-alanine
XYUPSBLFPTWJLC-GSVOUGTGSA-N
Synonyms:
D-strombine, N-(carboxymethyl)-D-Ala, N-[1-(R)-(Carboxy)ethyl]-(S)-Gly, strombine
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
glycine + pyruvate + NADH + H+ = N-(carboxymethyl)-D-alanine + NAD+ + H2O
show the reaction diagram
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-

Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Gly + pyruvate + NADH = Strombine + NAD+ + H2O
show the reaction diagram
-
Gly + pyruvate + NADH = N-(carboxymethyl)-D-alanine + NAD+
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
4.99
-
apparent value, isozyme St/AlDH1, with 1 mM NAD+, in 0.1 M PIPES-NaOH (pH 9.1), at 30°C

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
9.17
-
apparent value, isozyme St/AlDH1, with 1 mM NAD+, in 0.1 M PIPES-NaOH (pH 9.1), at 30°C

References & Links

Links to other databases for N-(carboxymethyl)-D-alanine

ChEBI
PubChem
ChEBI
PubChem