Ligand Val-Pro-Arg-7-amido-4-methylcoumarin

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Basic Ligand Information

Molecular Structure
Picture of Val-Pro-Arg-7-amido-4-methylcoumarin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C26H37N7O5
Val-Pro-Arg-7-amido-4-methylcoumarin
CCOBFOPWDBZKQO-IPJJNNNSSA-N
Synonyms:
Val-Pro-Arg-4-methylcoumarin-7-amide, Val-Pro-Arg-4-methylcoumarin 7-amide, Val-Pro-Arg 4-methylcoumarin 7-amide, VPR-7-amido-4-methylcoumarin, VPR-amido-4-methylcoumarin

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
VPR-amido-4-methylcoumarin + H2O = VPR + 7-amino-4-methylcoumarin
show the reaction diagram
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Val-Pro-Arg 4-methylcoumarin 7-amide + H2O = ?
show the reaction diagram
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Val-Pro-Arg-7-amido-4-methylcoumarin = Val-Pro-Arg + 7-amino-4-methylcoumarin
show the reaction diagram
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VPR-7-amido-4-methylcoumarin + H2O = VPR + 7-amino-4-methylcoumarin
show the reaction diagram
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VPR-amido-4-methylcoumarin + H2O = VPR + 7-amino-4-methylcoumarin
show the reaction diagram
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Val-Pro-Arg-7-amido-4-methylcoumarin + H2O = Val-Pro-Arg + 7-amino-4-methylcoumarin
show the reaction diagram
-
Val-Pro-Arg-4-methylcoumarin-7-amide + H2O = ?
show the reaction diagram
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.0075
-
37C, pH 7.5
0.0013
-
purified hK6
0.033
-
pH 8.0, 37C
0.45
-
20 mM Tris, 150 mM NaCl, 0.01% Tween 20 (pH7.5), 37C

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.28
-
37C, pH 7.5
0.36
-
purified hK6
0.049
-
pH 8.0, 37C
0.28
-
20 mM Tris, 150 mM NaCl, 0.01% Tween 20, pH 7.5, 37C

References & Links

Links to other databases for Val-Pro-Arg-7-amido-4-methylcoumarin

ChEBI
PubChem
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PubChem