Ligand 1-O-hexadecyl-sn-glycero-3-phosphocholine

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Basic Ligand Information

Molecular Structure
Picture of 1-O-hexadecyl-sn-glycero-3-phosphocholine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C24H52NO6P
1-O-hexadecyl-sn-glycero-3-phosphocholine
VLBPIWYTPAXCFJ-XMMPIXPASA-O
Synonyms:
1-hexadecyl-2-lyso-sn-glycero-3-phosphocholine, 1-hexadecyl-lyso-sn-glycero-3-phosphocholine, 1-hexadecyl-sn-glycero-3-phosphocholine, 1-O-hexadecyl-2-hydroxy-sn-glycero-3-phosphocholine, 1-O-hexadecyl-2-lyso-glycerophosphorylcholine, 1-O-Hexadecyl-2-lyso-sn-glycero-3-phosphocholine, 1-O-hexadecyl-sn-glycerol-3-phosphocholine, 1-palmityl-lysophosphatidylcholine, hexadecyl-lyso-sn-glycero-3-phosphocholine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-O-hexadecyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + CoA
show the reaction diagram
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2-acetyl-1-hexadecyl-sn-glycero-3-phosphocholine + 1-O-hexadecyl-sn-glycero-3-phosphocholine = 1-hexadecyl-sn-glycero-3-phosphocholine + 2-acetyl-1-hexadecyl-sn-glycero-3-phosphocholine
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-O-hexadecyl-sn-glycero-3-phosphocholine + 6-methyl-5,6,7,8-tetrahydropterin + O2 = ?
show the reaction diagram
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arachidonoyl-CoA + 1-O-hexadecyl-sn-glycero-3-phosphocholine = CoA + 2-arachidonoyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
show the reaction diagram
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1-O-hexadecyl-2-hydroxy-sn-glycero-3-phosphocholine + H2O = 1-(1-hexadecyl)-sn-glycero-3-phosphate + choline
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.1282
-
apparent KM
0.0267
-
Vmax is 0.29 micromol/min/mg, lysoPLD activity is more than twice that observed with 1-palmitoyl-glycerophoshorylcholine

References & Links

Links to other databases for 1-O-hexadecyl-sn-glycero-3-phosphocholine

ChEBI
PubChem
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PubChem