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Ligand beta-L-galactose 1-phosphate

Basic Ligand Information

Molecular Structure

Related pathways

Show all BRENDA pathways known for beta-L-galactose 1-phosphate

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Natural Substrate (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

3.1.3.93

beta-L-galactose 1-phosphate + H2O = L-galactose + phosphate

751922, 749997, 775161

-

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

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Show Natural Product (2 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.7.7.69

GDP-beta-L-galactose + alpha-D-mannose 1-phosphate = beta-L-galactose 1-phosphate + GDP-alpha-D-mannose

-

-

2.7.7.69

GDP-beta-L-galactose + phosphate = GDP + beta-L-galactose 1-phosphate

-

-

2.7.7.69

2 entries

Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Substrate (2 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.7.7.30

GTP + beta-L-galactopyranose 1-phosphate = GDP-beta-L-galactopyranose + diphosphate

706511

-

3.1.3.93

beta-L-galactose 1-phosphate + H2O = L-galactose + phosphate

716731, 727192, 716596, 751922, 749997, 775161

-

Product in Enzyme-catalyzed Reactions (3 results)

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Show Product (3 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.7.1.52

ATP + L-galactose = ADP + beta-L-galactose 1-phosphate

-

-

2.7.7.69

GDP-beta-L-galactose + alpha-D-mannose 1-phosphate = beta-L-galactose 1-phosphate + GDP-alpha-D-mannose

-

-

2.7.7.69

GDP-beta-L-galactose + phosphate = GDP + beta-L-galactose 1-phosphate

-

-

2.7.7.69

2 entries

Enzyme Kinetic Parameters

K_M Value (5 results)

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Show KM Value (5 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

3.1.3.93

0.01

-

pH 7.0, 30°C, 1.8 mM Mg2+, native enzyme

716731

3.1.3.93

0.022

-

pH 7.0, 30°C, 4.8 mM Mg2+

716731

3.1.3.93

0.044

-

pH 7.0, 30°C, 2 mM Mg2+

716731

3.1.3.93

0.107

-

pH 7.5, 22°C

716596

3.1.3.93

0.15

-

pH 7.0, 30°C, recombinant enzyme

716731

3.1.3.93

5 entries

References & Links

Literature References (8)

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Show Reference (8 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

706511

19805264

Chemoenzymatic synthesis of GDP-L-fucose and the Lewis X glycan derivatives

2009

Wang, W.; Hu, T.; Frantom, P.A.; Zheng, T.; Gerwe, B.; Del Amo, D.S.; Garret, S.; Seidel, R.D.; Wu, P.

Proc. Natl. Acad. Sci. USA

106

16096-16101

716596

19339506

VTC4 is a bifunctional enzyme that affects myoinositol and ascorbate biosynthesis in plants

2009

Torabinejad, J.; Donahue, J.L.; Gunesekera, B.N.; Allen-Daniels, M.J.; Gillaspy, G.E.

Plant Physiol.

150

951-961

716731

15550539

A highly specific L-galactose-1-phosphate phosphatase on the path to ascorbate biosynthesis

2004

Laing, W.A.; Bulley, S.; Wright, M.; Cooney, J.; Jensen, D.; Barraclough, D.; MacRae, E.

Proc. Natl. Acad. Sci. USA

101

16976-16981

727192

22790939

Molecular cloning and characterization of L-galactose-1-phosphate phosphatase from tobacco (Nicotiana tabacum)

2012

Sakamoto, S.; Fujikawa, Y.; Tanaka, N.; Esaka, M.

Biosci. Biotechnol. Biochem.

76

1155-1162

749997

-

Gene expression and enzyme activities of the D-mannose/L-galactose pathway influence L-ascorbic acid content in Myrciaria dubia

2015

Castro, J.; Cobos, M.; Maddox, J.; Iman, S.; Egoavil, A.; Torres, J.; Gutierrez, F.

Biol. Plant.

59

783-787

751922

25938231

Manipulation of the rice L-galactose pathway evaluation of the effects of transgene overexpression on ascorbate accumulation and abiotic stress tolerance

2015

Zhang, G.Y.; Liu, R.R.; Zhang, C.Q.; Tang, K.X.; Sun, M.F.; Yan, G.H.; Liu, Q.Q.

PLoS ONE

10

e0125870

751922

25938231

Manipulation of the rice L-galactose pathway evaluation of the effects of transgene overexpression on ascorbate accumulation and abiotic stress tolerance

2015

Zhang, G.Y.; Liu, R.R.; Zhang, C.Q.; Tang, K.X.; Sun, M.F.; Yan, G.H.; Liu, Q.Q.

PLoS ONE

10

e0125870

751922

2 entries

775161

36356544

Over-expression of GGP1 and GPP genes enhances ascorbate content and nutritional quality of tomato

2022

Koukounaras, A.; Mellidou, I.; Patelou, E.; Kostas, S.; Shukla, V.; Engineer, C.; Papaefthimiou, D.; Amari, F.; Chatzopoulos, D.; Mattoo, A.K.; Kanellis, A.K.

Plant Physiol. Biochem.

193

124-138

Links to other databases for beta-L-galactose 1-phosphate

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Show Links (1 entry)