Ligand N-methyl L-aspartate

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Basic Ligand Information

Molecular Structure
Picture of N-methyl L-aspartate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H9NO4
N-methyl L-aspartate
HOKKHZGPKSLGJE-VKHMYHEASA-N
Synonyms:
(2S)-N-methylaspartic acid, N-methyl-L-aspartate, N-methylaspartic acid, Nalpha-methyl-L-Asp

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N-methyl-L-aspartate + H2O + O2 = ?
show the reaction diagram
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N-methyl L-aspartate + 2,6-dichlorophenolindophenol + H2O = L-aspartate + formaldehyde + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
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(2S)-N-methylaspartic acid = fumarate + methylamine
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Nalpha-methyl-L-Asn + H2O = Nalpha-methyl-L-Asp + NH3
show the reaction diagram
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methylamine + fumarate = N-methylaspartic acid
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
at 1 mM methyl-DL-aspartic acid the enzyme activity is reduced by about 60%, while at 5 mM the catalytic activity is completely abolished
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Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.3
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References & Links

Links to other databases for N-methyl L-aspartate

ChEBI
PubChem
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PubChem