Ligand dimethylamine

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Basic Ligand Information

Molecular Structure
Picture of dimethylamine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C2H7N
dimethylamine
ROSDSFDQCJNGOL-UHFFFAOYSA-N
Synonyms:
(CH3)2NH, N,N-dimethylamine, secondary amine

Show all pahtways known for Show all pathways known for dimethylamine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dimethylamine + NADPH + H+ + O2 = methylamine + formaldehyde + NADP+ + H2O
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N,N-dimethylformamide + H2O = dimethylamine + formate
show the reaction diagram
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Trimethylamine N-oxide = Dimethylamine + formaldehyde
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Substrate in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N,N-dimethylamine + NADPH + H+ + O2 = N,N-dimethylamine N-oxide + NADP+ + H2O
show the reaction diagram
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secondary amine + NADPH + O2 = secondary nitrone + NADP+ + H2O
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Product in Enzyme-catalyzed Reactions (27 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N,N-dimethylhydroxylamine + NADH = dimethylamine + NAD+ + H2O
show the reaction diagram
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N,N-dimethylcaproamide + H2O = dimethylamine + hexanoate
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N-dimethylammelide + H2O = cyanuric acid + dimethylamine
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Trimethylamine N-oxide = Dimethylamine + formaldehyde
show the reaction diagram
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(2S)-N,N-dimethylaspartic acid = fumarate + dimethylamine
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Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
10 mM, 23% inhibition
-
uncompetitive inhibitor
-
reaction of component I with NH4+ as substrate
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Enzyme Kinetic Parameters

KM Value (5 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0897
-
recombinant enzyme, in 80 mM PIPES buffer (pH 7.6), at 22C
0.0156
-
-

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
6
-
pH 8.0, 25C

References & Links

Links to other databases for dimethylamine

ChEBI
PubChem
ChEBI
PubChem