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Ligand methylthioacetate Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C3 H6 O2 S
methylthioacetate
HGTBAIVLETUVCG-UHFFFAOYSA-N
(methylsulfanyl)acetate, (methylthio)acetic acid, 2-(methylthio)acetic acid, methanethioacetate, methylmercaptoacetate, methylthioacetic acid, S-methylethanethioate, S-methylmercaptoacetic acid, S-methylthioglycolate
Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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dimethylthetin + L-homocysteine = S-methylthioglycolate + L-methionine
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Product in Enzyme-catalyzed Reactions (12 results)
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dimethylsulfonioacetate + DL-homocysteine = (methylsulfanyl)acetate + L-methionine
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dimethylthetin + L-homocysteine = S-methylthioglycolate + L-methionine
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ethanethioic S-acid + S-adenosyl-L-methionine = S-methylethanethioate + S-adenosyl-L-homocysteine
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mercaptoacetic acid + S-adenosyl-L-methionine = S-methylmercaptoacetic acid + S-adenosyl-L-homocysteine
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methanethiol + acetyl-CoA = methanethioacetate + coenzyme A
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fluorescein-3',6'-bis(oxy)methylene bis[(methylsulfanyl)acetate] + H2O = fluorescein-3'-oxymethyl (methylsulfanyl)acetate + (methylsulfanyl)acetate
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fluorescein-3',6'-bis(oxy)methylene bis[(methylsulfanyl)acetate] + H2O = fluorescein-3'-oxymethyl (methylsulfanyl)acetate + (methylsulfanyl)acetate
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methyl-mercaptoacetyl-DL-alanine + H2O = methylmercaptoacetate + DL-alanine
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methylmercaptoacetyl-DL-phenylalanine + H2O = methylmercaptoacetate + DL-phenylalanine
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(methylthio)acetonitrile + H2O = (methylthio)acetic acid + NH3
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(methylthio)acetonitrile + H2O = 2-(methylthio)acetic acid + NH3
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methylthioacetonitrile + H2O = methylthioacetic acid + NH3
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Inhibitor in Enzyme-catalyzed Reactions (9 results)
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comparison of complexes with wild-type and mutant Y317F
comparison of complexes with wild-type and mutant Y317F
comparison of complexes with wild-type and mutant Y317F
3D Structure of Enzyme-Ligand-Complex (PDB) (30 results)
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Enzyme Kinetic Parameters
References & Links Literature References (6)
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Thetin-homocysteine transmethylase: some further characteristics of the enzyme from rat liver
1958
Maw, G.A.
Biochem. J.
70
168-173
Thetin-homocysteine transmethylase: a preliminary manometric study of the enzyme from rat liver
1956
Maw, G.A.
Biochem. J.
63
116-124
The EstA esterase is responsible for the main capacity of Lactococcus lactis to synthesize short chain fatty acid esters in vitro
2002
Nardi, M.; Fiez-Vandal, C.; Tailliez, P.; Monnet, V.
J. Appl. Microbiol.
93
994-1002
Ionization of zwitterionic amine substrates bound to monomeric sarcosine oxidase
2005
Zhao, G.; Jorns, M.S.
Biochemistry
44
16866-16874
Arginine 49 is a bifunctional residue important in catalysis and biosynthesis of monomeric sarcosine oxidase: a context-sensitive model for the electrostatic impact of arginine to lysine mutations
2008
Hassan-Abdallah, A.; Zhao, G.; Chen, Z.W.; Mathews, F.S.; Schuman Jorns, M.
Biochemistry
47
2913-2922
Identification of the oxygen activation site in monomeric sarcosine oxidase: role of lys265 in catalysis
2008
Zhao, G.; Bruckner, R.C.; Jorns, M.S.
Biochemistry
47
9124-9135
Links to other databases for methylthioacetate