Ligand diethyl ether

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Basic Ligand Information

Molecular Structure
Picture of diethyl ether (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H10O
diethyl ether
RTZKZFJDLAIYFH-UHFFFAOYSA-N
Synonyms:
diethylether, ether, ethyl ether

Show all pahtways known for Show all pathways known for diethyl ether

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
diethyl ether + NAD(P)H + O2 = ethanol + ethanal + NAD(P)+ + H2O
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
10% v/v, 2.6fold activation
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dramatic increase in the phosphorylation level of Ser9 of TPKI/GSK3beta immediately and 10 min after ether administration, followed by rapid virtual reversion to baseline by 20 min, no significant changes in the protein level or Tyr216 phosphorylation level of the enzyme
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slight activation at 1-3% v/v
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stimulates
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hydrolysis activity is enhanced in the presence of non-acceptor type organic solvents such as hexane, cyclohexane, diethylether, and acetone
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cell-bound PVA activity shows an eightfold increase upon treatment with diethylether at 0.010 ml/mg dry biomass for 45 min upon permeabilization
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strongly activates
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Inhibitor in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
73% residual activity after 30 min incubation at 30% (v/v)
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strong inhibition
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25% v/v, 22% inhibition
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Enzyme Kinetic Parameters

References & Links

Links to other databases for diethyl ether

ChEBI
PubChem
ChEBI
PubChem