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Ligand 31-norcycloartenol

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (3 results)

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Show Substrate (3 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.1.1.142

31-norcycloartenol + S-adenosyl-L-methionine = 24-methylene-31-norcycloartenol + S-adenosyl-L-homocysteine

485322

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2.1.1.142

31-norcycloartenol + S-adenosyl-L-methionine = ?

657661

-

2.1.1.142

S-adenosyl-L-methionine + 31-norcycloartenol = S-adenosyl-L-homocysteine + ?

659247, 288661

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2.1.1.142

3 entries

Product in Enzyme-catalyzed Reactions (1 result)

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Show Product (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

5.4.99.8

1-trans-1'-Norsqualene-2,3-epoxide = 31-Norcycloartenol

3621

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Enzyme Kinetic Parameters

K_M Value (4 results)

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Show KM Value (4 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

2.1.1.142

0.03

-

pH 7.5, 35°C

657661

2.1.1.142

0.032

-

-

659247

2.1.1.142

0.036

-

-

485322

2.1.1.142

0.61

-

-

288661

2.1.1.142

4 entries

References & Links

Literature References (5)

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Show Reference (5 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

3621

-

Cyclisation of 1-trans-1'-norsqualene-2,3-epoxide and 1-cis-1'-norsqualene-2,3-epoxide by a cell free system of corn embryos

1976

Cattel, L.; Anding, C.; Benveniste, P.

Phytochemistry

15

931-935

288661

10882005

Sterol C-methyl transferase from Prototheca wickerhamii mechanism, sterol specificity and inhibition

2000

Mangla, A.T.; Nes, W.D.

Bioorg. Med. Chem.

8

925-936

485322

1869550

Structural requirements for transformation of substrates by the (S)-adenosyl-L-methionine:delta 24(25)-sterol methyl transferase

1991

Nes, W.D.; Janssen, G.G.; Bergenstrahle, A.

J. Biol. Chem.

266

15202-15212

657661

14622971

Sterol methyltransferase2: purification, properties, and inhibition

2003

Zhou, W.; Nes, W.D.

Arch. Biochem. Biophys.

420

18-34

659247

12807886

Biosynthesis of phytosterols. Kinetic mechanism for the enzymatic C-methylation of sterols

2003

Nes, W.D.; Song, Z.; Dennis, A.L.; Zhou, W.; Nam, J.; Miller, M.B.

J. Biol. Chem.

278

34505-34516

Links to other databases for 31-norcycloartenol

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Show Links (1 entry)

ChEBI

PubChem

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